Varuna (Crataeva nurvala) is a medicinal plant widely used in traditional Ayurvedic medicine. Its use for gastrointestinal disorders, including colitis, is primarily rooted in tradition rather than robust scientific research. In Ayurveda, Varuna is classified as a herb with anti-inflammatory, laxative, and detoxifying properties. It is sometimes recommended for conditions involving gut inflammation, such as colitis, due to its perceived ability to reduce "pitta" (heat/inflammation) and to support the health of the digestive tract.

The traditional use of Varuna for colitis is mainly based on its general role in managing urinary and digestive system disorders, rather than direct evidence or clinical studies targeting colitis. While some preclinical studies have explored the anti-inflammatory and antioxidant effects of Varuna extracts, these are limited and mostly conducted in animal models or in vitro settings.

There are currently no well-designed clinical trials or substantial scientific evidence specifically validating the efficacy or safety of Varuna in the management of colitis in humans. Therefore, its use for this indication remains primarily traditional, with a low level of evidence (rated 2/5), and should be approached with caution until more rigorous research is available.