Evidence supporting the use of: Flavones (various)
For the health condition: Colon (spastic)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flavones are a class of polyphenolic compounds found in a variety of plants, including parsley, celery, and chamomile. There is some scientific evidence suggesting that flavones may have beneficial effects on colon health, particularly in cases of spastic colon (also known as irritable bowel syndrome, IBS). Preclinical studies have demonstrated that certain flavones, such as apigenin and luteolin, possess anti-inflammatory, antispasmodic, and antioxidant properties. These effects are thought to modulate intestinal motility and reduce smooth muscle contractions, which could help alleviate symptoms associated with spastic colon.

Limited clinical evidence is available, with small trials and animal studies indicating that flavone-rich extracts can reduce gut inflammation and smooth muscle spasms. For example, chamomile, which contains notable amounts of flavones, has shown mild efficacy in reducing abdominal cramping and discomfort in IBS patients in some studies. However, most available data come from in vitro or animal models, and well-controlled human trials are lacking.

In summary, while there is a plausible scientific rationale and some early evidence supporting the use of flavones for spastic colon, the overall quality and quantity of clinical evidence is limited. Therefore, the evidence level is rated as 2 out of 5.

More about Flavones (various)
More about Colon (spastic)

Products containing Flavones (various)

We currently have no products on Vitabase that contain this ingredient.