Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Hydroxyanthracene derivatives (such as those found in senna, cascara, and aloe) have a long-standing traditional use as stimulant laxatives to treat constipation, including cases where the colon exhibits spasticity (spastic colon, sometimes associated with irritable bowel syndrome). Traditional herbal medicine systems, particularly in Europe and Asia, have used these plant extracts to promote bowel movements for centuries. The mechanism is thought to involve stimulation of peristalsis and decreased water reabsorption in the colon via direct action on the intestinal mucosa. However, while there is strong traditional use, scientific validation for their efficacy specifically in “spastic colon” is limited. Most clinical trials and pharmacological studies focus on general constipation, not specifically on spastic disorders of the colon. Furthermore, stimulant laxatives can sometimes worsen cramping, which is a hallmark of spastic colon, and guidelines often recommend caution or avoidance in these cases. In summary, hydroxyanthracene derivatives are traditionally used for various types of constipation, including spastic colon, but the scientific evidence for this specific indication is weak. Most regulatory and clinical guidelines now caution against their long-term use due to potential adverse effects and lack of robust clinical evidence for chronic or spastic conditions.

More about Hydroxyanthracene
More about Colon (spastic)

Other ingredients used for Colon (spastic)

aloe vera
anthocyanins
turmeric
fennel
garlic bulb
ginger
green tea
licorice root
pomegranate
Alexandrian senna

Other health conditions supported by Hydroxyanthracene

Colon (atonic)
Colon (spastic)
Constipation (adults)
Constipation (children)

Products containing Hydroxyanthracene

We currently have no products on Vitabase that contain this ingredient.