Evidence supporting the use of: Salidrosides
For the health condition: Concentration (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Salidroside is a primary active compound found in Rhodiola rosea, a traditional adaptogenic herb. Its use for supporting concentration and cognitive function has both historical roots and emerging scientific evidence, though the strength of the evidence is moderate. Preclinical studies (in vitro and animal models) have demonstrated that salidroside may exert neuroprotective effects, enhance synaptic plasticity, and reduce fatigue-induced cognitive impairments. Some clinical studies involving Rhodiola rosea extracts (which contain salidroside along with other compounds) have shown improvements in mental performance, attention, and reduced mental fatigue in stressful situations. For example, several small randomized controlled trials have reported improvements in attention, accuracy, and work capacity in subjects under fatigue or stress.

However, it is important to note that most human studies have evaluated whole Rhodiola extracts rather than isolated salidroside. The specificity of salidroside's effect on concentration in humans remains less clear, and high-quality, large-scale clinical trials with isolated salidroside are lacking. Thus, while there is some scientific rationale and preliminary evidence supporting its use for poor concentration—primarily based on traditional use and the results of studies with Rhodiola extracts—the direct evidence for isolated salidroside is limited.

In summary, the use of salidroside for poor concentration is supported by a mix of traditional use and modest scientific evidence, but more rigorous research is needed to establish its efficacy and mechanism of action in humans.

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Products containing Salidrosides

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