Evidence supporting the use of: Sulbutiamine
For the health condition: Concentration (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) that has been studied for its potential to improve cognitive function, including concentration. Some scientific evidence suggests that sulbutiamine may enhance aspects of cognitive performance, particularly in individuals with fatigue or certain neurological conditions. Several small clinical studies and open-label trials have reported improvements in attention, memory, and alertness among patients with asthenia (a condition characterized by physical weakness and mental fatigue), as well as in some cases of mild cognitive impairment. The proposed mechanisms involve increased cholinergic and glutamatergic transmission in the brain and improved thiamine utilization, which may support neuronal function.

However, the overall quality and quantity of evidence specifically addressing sulbutiamine's effects on concentration in healthy individuals is limited. Most studies have small sample sizes, lack rigorous controls, or focus on populations with underlying medical issues rather than the general population experiencing poor concentration. There is a lack of large-scale, placebo-controlled trials directly measuring concentration outcomes. As such, while there is some scientific support for its use, the evidence is not robust, and the effect size remains uncertain.

In summary, sulbutiamine has a plausible scientific rationale and some clinical backing for supporting concentration, particularly in cases linked to fatigue or neurological impairment, but the existing evidence is moderate at best and further research is needed to establish its efficacy for this specific purpose.

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Products containing Sulbutiamine

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