Evidence supporting the use of: Aniracetam
For the health condition: Confusion

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Aniracetam is a member of the racetam family of nootropic compounds, initially developed in the 1970s. Its primary use has been in cognitive enhancement, with some studies investigating its effects on cognitive deficits such as confusion, memory impairment, and attention problems, especially in elderly populations or those with cognitive disorders. Scientific evidence for Aniracetam’s use in treating confusion is limited but present; a handful of small-scale clinical trials and animal studies have reported beneficial effects on cognitive function, including improvements in attention, memory, and reduction of behavioral disturbances in elderly patients with dementia or cerebrovascular disease.

For example, some studies conducted in Europe and Japan in the 1980s and 1990s suggested that Aniracetam could improve symptoms of cognitive decline, including confusion, when compared to placebo. Proposed mechanisms for these effects include modulation of glutamatergic and cholinergic neurotransmission. However, these studies tended to be small, short-term, and sometimes methodologically limited. There is a lack of large, rigorous, modern clinical trials to firmly establish Aniracetam’s efficacy for confusion. Regulatory bodies such as the FDA have not approved Aniracetam for cognitive disorders, citing insufficient evidence. In summary, while there is some scientific basis for Aniracetam’s use to support or treat confusion, the evidence is modest and not conclusive.

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Products containing Aniracetam

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