Evidence supporting the use of: Vasicine
For the health condition: Congestion

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vasicine is an alkaloid extracted from the plant Adhatoda vasica, commonly known as Malabar nut. Its use for treating or supporting congestion is backed by both traditional Ayurvedic practices and a moderate amount of scientific research. Several preclinical studies have demonstrated that vasicine exhibits bronchodilatory and expectorant properties. For example, animal studies have shown that vasicine can relax the bronchial smooth muscles, enhance mucociliary clearance, and facilitate the removal of sputum. These effects are believed to be mediated through inhibition of phosphodiesterase and stimulation of the respiratory tract’s secretory cells, thereby thinning and loosening mucus. Moreover, vasicine has been shown to have mild anti-inflammatory and antimicrobial properties, which may further contribute to its efficacy in respiratory conditions with congestion.

While clinical evidence in humans is limited and mostly derived from studies involving polyherbal formulations that include vasicine, the traditional use and consistent preclinical data support its use for respiratory congestion. Therefore, the evidence level is moderate (rated 3/5), as more robust human clinical trials are needed to establish definitive efficacy and safety profiles for vasicine as a standalone treatment for congestion.

More about Vasicine
More about Congestion

Products containing Vasicine

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