Evidence supporting the use of: Adrenergic amines
For the health condition: Congestion (bronchial)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Adrenergic amines, such as epinephrine and related compounds (including pseudoephedrine and phenylephrine), are well-established agents in the treatment of bronchial congestion. These compounds exert their effects by stimulating adrenergic receptors, particularly the alpha and beta receptors in the respiratory tract. Activation of these receptors leads to vasoconstriction (via alpha receptors) and bronchodilation (via beta-2 receptors), which reduces mucosal edema and opens up the airways, providing symptomatic relief from congestion.
Numerous clinical studies and decades of medical use have validated the efficacy of adrenergic amines in managing symptoms of bronchial congestion, particularly in acute settings such as asthma exacerbations or allergic reactions. For example, inhaled beta-agonists (like albuterol, a selective beta-2 adrenergic agonist) are frontline therapies for bronchospasm and associated congestion. Oral and topical forms of adrenergic amines such as pseudoephedrine and phenylephrine are commonly used as decongestants in over-the-counter cold and flu preparations.
However, the use of non-selective adrenergic amines carries risks, such as increased heart rate, hypertension, and central nervous system stimulation, which limits their use in certain populations. Despite these risks, the therapeutic rationale and mechanism of action for adrenergic amines in treating bronchial congestion are well understood and supported by significant scientific evidence.
More about Adrenergic amines
More about Congestion (bronchial)
Other ingredients used for Congestion (bronchial)
allspicealoe vera
alpha-pinene
waterhyssop
basil
benegut perilla (proprietary)
beta-pinene
black cumin
black currant
black pepper
Indian frankincense
bupleurum falcatum
bасора
caffeine
capsaicinoids
chamomile
chen pi
Chinese salvia root
clove
Coptis chinensis
cowage seed
turmeric
echinacea purpurea
elderberry
ethanol
forsythia
garlic bulb
ginger
grape
onion
green tea
horseradish
Indian tinospora
licorice root
lovage
mustard seed
n-acetyl-cysteine (NAC)
spruce
ophiopogon root
oregano
perilla
phellodendron amurense
platycodon root
pomegranate
quercetin
rosemary
scrophularia root
shiitake mushroom
spearmint leaf
sphaeranthus indicus
thyme
vitamin C
yellow root
squawvine
boneset
mullein
hyssop
cardamom
atractylodes
capsicum
mugwort
malabar nut
alpinia galangal
ferula assafoetida
inula racemosa
anise
blackboard tree
lingusticum wallichii
buckthorn
fritillaria
lemongrass
yerba santa
elecampane
coltsfoot
chrysanthemum
juniper berries
siler root
sweet flag
oriental arborvitae
trichosanthes
zanthoxylum
eucalyptus
menthol oil
aster root
abies spectabilis
horehound
Sichuan pepper
cayenne pepper
soursop
Alcohol
Agastache
Anamarrhena
Alpha-terpineol
Ardisia
Angelica
Allicin
Asarum heterotropoides
Aconite
Asafoetida
Andrographolide
Adrenergic amines
Asteracea
Allyl Sulfide
Adenophora
Allium tuberosum
Amor seco
Arisaema
Asarum sieboldii
Alantolactone
Atractylone
Black Seed
Baikal Skullcap
Baphicacanthus cusia
Bidens pilosa
Black spruce
Bicarbonate
Blepharis
Balsam
Bishop's Weed
Boswellic Acid
Bayleaf
Black galingale
Barleria
Bitter Grass
Bisabolene
Bael
berry
Boswellia
Baccharoides anthelmintica
black salt
Bee products
Bombax
Buddha's Hand
Borage
Bupleurum
Balloon Flower
Belamcanda
Borneol
Camellia sinensis
Chinese Silkvine
Curry leaf
Chinese Mountain Ant
Clerodendrum trichotomum
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Cowherb
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Cinnamaldehyde
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Diterpenes
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Echinacea
Elder
Essential Oil Blend
Ephedrine
Fang-Feng
Fernbush
Galangal
Ivy
Mustard
Mallow
Sandalwood
Vervain
Other health conditions supported by Adrenergic amines
Allergies (respiratory)Asthma
Attention Deficit Disorder
Bedwetting
Bites and Stings
Bronchitis
Cardiac Arrest
Cardiovascular Disease
Chest Pain
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Congestion (bronchial)
Congestion (sinus)
Hypotension
Narcolepsy
Weight Loss