Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Fritillaria, particularly the bulbs of Fritillaria cirrhosa and Fritillaria thunbergii, has a long history of use in Traditional Chinese Medicine (TCM) for treating respiratory conditions, especially bronchial congestion, coughs, and phlegm. In TCM, fritillaria is known as "Chuan Bei Mu" or "Zhe Bei Mu" and is classified as having properties that clear heat and transform phlegm. Historical texts and modern herbal compendia frequently list fritillaria as an expectorant and antitussive, citing its ability to help loosen and expel mucus from the bronchial passages, thus alleviating congestion. The traditional rationale is supported by centuries of clinical use and inclusion in many classic TCM formulations for respiratory ailments. Some contemporary laboratory studies have identified bioactive compounds in fritillaria, such as peimine and peiminine, which exhibit anti-inflammatory and cough-suppressing effects in animal models. However, robust clinical trials in humans are limited, and much of the support remains anecdotal or based on historical practice rather than modern scientific validation. In summary, the use of fritillaria for bronchial congestion is primarily justified by traditional medicine, with moderate evidence from laboratory studies but insufficient large-scale clinical trials to fully support its efficacy by Western scientific standards. Those considering fritillaria should consult healthcare professionals, especially due to potential toxicity with excessive use.

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