Evidence supporting the use of: Vasicine
For the health condition: Congestion (bronchial)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Vasicine is an alkaloid derived from the plant Justicia adhatoda (also known as Vasaka or Malabar nut), a traditional medicinal herb used extensively in Ayurveda and other traditional medicine systems for respiratory ailments. The scientific basis for its use in treating bronchial congestion lies in its well-documented bronchodilator and expectorant properties. Several pharmacological studies have demonstrated that vasicine can relax the bronchial smooth muscles, leading to bronchodilation, which facilitates easier breathing in individuals with respiratory congestion. Additionally, vasicine increases the volume of bronchial secretions, helping to loosen and expel mucus, thus clearing the airways.
Animal studies and limited clinical investigations have reported that vasicine exhibits significant expectorant activity, comparable to or sometimes exceeding that of standard drugs like bromhexine. Vasicine has also been found to possess mild antitussive (cough-suppressant) and anti-inflammatory activities, further supporting its application in respiratory conditions involving congestion. However, most of the available data are derived from preclinical studies and small-scale human trials, with a relative lack of large, rigorous clinical trials to provide high-level evidence. Despite this, its consistent use in traditional medicine, backed by plausible pharmacological mechanisms and early scientific studies, supports a moderate evidence rating for its use in bronchial congestion.
Other ingredients used for Congestion (bronchial)
allspicealoe vera
alpha-pinene
waterhyssop
basil
benegut perilla (proprietary)
beta-pinene
black cumin
black currant
black pepper
Indian frankincense
bupleurum falcatum
bасора
caffeine
capsaicinoids
chamomile
chen pi
Chinese salvia root
clove
Coptis chinensis
cowage seed
turmeric
echinacea purpurea
elderberry
ethanol
forsythia
garlic bulb
ginger
grape
onion
green tea
horseradish
Indian tinospora
licorice root
lovage
mustard seed
n-acetyl-cysteine (NAC)
spruce
ophiopogon root
oregano
perilla
phellodendron amurense
platycodon root
pomegranate
quercetin
rosemary
scrophularia root
shiitake mushroom
spearmint leaf
sphaeranthus indicus
thyme
vitamin C
yellow root
squawvine
boneset
mullein
hyssop
cardamom
atractylodes
capsicum
mugwort
malabar nut
alpinia galangal
ferula assafoetida
inula racemosa
anise
blackboard tree
lingusticum wallichii
buckthorn
fritillaria
lemongrass
yerba santa
elecampane
coltsfoot
chrysanthemum
juniper berries
siler root
sweet flag
oriental arborvitae
trichosanthes
zanthoxylum
eucalyptus
menthol oil
aster root
abies spectabilis
horehound
Sichuan pepper
cayenne pepper
soursop
Alcohol
Agastache
Anamarrhena
Alpha-terpineol
Ardisia
Angelica
Allicin
Asarum heterotropoides
Aconite
Asafoetida
Andrographolide
Adrenergic amines
Asteracea
Allyl Sulfide
Adenophora
Allium tuberosum
Amor seco
Arisaema
Asarum sieboldii
Alantolactone
Atractylone
Black Seed
Baikal Skullcap
Baphicacanthus cusia
Bidens pilosa
Black spruce
Bicarbonate
Blepharis
Balsam
Bishop's Weed
Boswellic Acid
Bayleaf
Black galingale
Barleria
Bitter Grass
Bisabolene
Bael
berry
Boswellia
Baccharoides anthelmintica
black salt
Bee products
Bombax
Buddha's Hand
Borage
Bupleurum
Balloon Flower
Belamcanda
Borneol
Camellia sinensis
Chinese Silkvine
Curry leaf
Chinese Mountain Ant
Clerodendrum trichotomum
Citrus
Cineole
Cajuput
Chinese Raisintree
Cowherb
Curcumen
Cistus
Curcuma
Calamus
Cinnamaldehyde
Carthamus
Culvers Root
Chondrus
Dragonhead
Diterpenes
Ephedra
European Elder
Eclipta
Echinacea
Elder
Essential Oil Blend
Ephedrine
Galangal
Ivy
Mustard
Mallow
Sandalwood
Vervain