Evidence supporting the use of: Vasicinone
For the health condition: Congestion (bronchial)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Vasicinone is a quinazoline alkaloid derived from the plant Adhatoda vasica (also known as Malabar nut or Vasaka), which has been used in traditional Ayurvedic and Unani medicine for centuries to treat respiratory ailments, including bronchial congestion. The use of Adhatoda vasica preparations for bronchial congestion is primarily supported by traditional practices, where the whole plant or its extracts are used to alleviate symptoms of cough, bronchitis, and asthma.

Phytochemical investigations have identified vasicinone as one of the major active constituents, alongside vasicine. Some pharmacological studies—mainly preclinical—suggest that vasicinone exhibits bronchodilatory, expectorant, and mild anti-inflammatory activities, which could theoretically help in relieving bronchial congestion. However, the majority of these studies are in vitro or animal-based, with limited translation to clinical efficacy in humans. There are no large, high-quality clinical trials directly evaluating isolated vasicinone for bronchial congestion.

Therefore, while there is a plausible pharmacological basis and a long history of traditional use for the parent plant and its extracts, the direct use and efficacy of purified vasicinone for bronchial congestion is not robustly established by modern clinical science. The evidence rating reflects strong tradition and some supportive preclinical data, but limited direct clinical validation.

More about Vasicinone
More about Congestion (bronchial)

Other ingredients used for Congestion (bronchial)

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Products containing Vasicinone

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