Evidence supporting the use of: Ligustrazin
For the health condition: Congestion (lungs)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Ligustrazin (also known as tetramethylpyrazine or TMP) is a bioactive compound extracted from the Chinese medicinal herb Ligusticum chuanxiong, which has been widely used in Traditional Chinese Medicine (TCM). Its use for treating or supporting lung congestion is primarily justified by traditional rather than scientific evidence. In TCM, Ligusticum chuanxiong is considered to promote blood circulation and remove blood stasis, and it has been traditionally prescribed to treat various cardiovascular and cerebrovascular conditions. Some TCM practices extend its use to relieve symptoms associated with lung congestion or respiratory disorders, often as part of multi-herb formulations targeting "Qi stagnation" or "phlegm dampness" in the lungs.
From a scientific perspective, studies on ligustrazin have primarily focused on its effects related to cardiovascular and cerebrovascular diseases, such as angina, stroke, and vascular dementia. There is limited preclinical evidence suggesting potential anti-inflammatory and vasodilatory effects that could theoretically benefit pulmonary circulation. However, robust clinical studies specifically supporting ligustrazin for lung congestion are lacking. Most available research does not directly address its efficacy for this indication, and its use remains rooted in traditional practice rather than validated by high-quality modern clinical trials.
In summary, ligustrazin's application for lung congestion is primarily based on traditional use, with only limited or indirect supportive evidence from scientific studies. Its use for this condition should be considered with caution and ideally within the framework of traditional medicine.
Other ingredients used for Congestion (lungs)
Abies spectabilisAconite
Adenophora
Agastache
Alantolactone
Allicin
Allium tuberosum
Allspice
Allyl isothiocyanate
Aloe vera
alpha-pinene
alpinia galangal
ambergris
Amor seco
andrographolide
Angelica
anise
Ardisia
Arisaema
asafoetida
Asarum heterotropoides
Asarum sieboldii
aster root
atractylodes
atractylone
Baccharoides anthelmintica
bael
Baikal Skullcap
balloon flower
balsam
Baphicacanthus cusia
Barleria
basil
bayleaf
bee hive
bee products
Belamcanda
benegut perilla (proprietary)
berry
beta-pinene
Bidens pilosa
bisabolene
bishop\'s weed
bitter grass
black cumin
black currant
black pepper
black salt
black seed
blackboard tree
Blepharis
Bombax
boneset
borage
borneol
Boswellia
Boswellic Acid
Buddha\'s hand
Bupleurum
bupleurum falcatum
bасора
cajuput
calamus
Camellia sinensis
capsaicinoids
capsicum
cardamom
Carthamus
cayenne pepper
chamomile
chen pi
Chinese raisintree
Chinese salvia root
Chinese silkvine
Chondrus
chrysanthemum
cineole
cinnamaldehyde
Cistus
Citrus
Clerodendrum trichotomum
clove
coltsfoot
Coptis chinensis
cowherb
culvers Root
curcumen
curry leaf
diterpenes
dragonhead
Echinacea
echinacea purpurea
Eclipta
Elder
elderberry
elecampane
Ephedra
ephedrine
essential oil blend
eucalyptus
European Elder
European five-finger grass
Evodia
fang-feng
fat liver oil
ferula assafoetida
flavoglycosides
forsythia
frankincense
fritillaria
Galangal
Gallesia
gamma-terpinene
Gardenia jasminoides
garlic bulb
ginger
Glycyrrhetinic acid
Gnaphalium
grape
green tea
Guaco
Heartsease
Hedyotis
Helicteres isora
honey
horehound
Horsemint
horseradish
Houttuynia
hyssop
Indian frankincense
Indian tinospora
inula racemosa
Isatis
Ivy
jungli-bean
juniper berries
Khella
labrador tea
Laggera pterodonta
Ledebouriella
lemongrass
lichen
licorice root
Ligusticum
Ligustrazin
limonene
Litsea
Lomatium
long pepper
lovage
lungwort
malabar nut
mallow
Meadow sage
Menthol oil
Methylxanthine
Monoterpenes
Mountain Pepper
Mucolase
Mugwort
Mullein
Mustard
mustard seed
Neoandrographolides
Nutmeg
onion
Ophiopogon
ophiopogon root
oregano
oriental arborvitae
Oroxylum indicum
Orris
Osha
Paris polyphylla
Pepper
perilla
Peucedanum
Phellodendron
phellodendron amurense
phenolic compounds
Pinellia ternata
Piper nigrum
Piper retrofractum
Platycodon
platycodon root
Pluchea
Polygonum
pomegranate
prepared aconite tuber
Pyrrosia
quercetin
ravinsara
rosemary
Rubiaceae
Sagebrush
Sambucus nigra
Sandalwood
scrophularia root
Servicetree
Sesquiterpenes
shiitake mushroom
Sichuan Lovage
Sichuan pepper
siler root
Smartweed
Solanum indicum
Sophora
spearmint leaf
Sphaeranthus indicus
spruce
squawvine
Stereospermum
Sulfated polysaccharide
Sundew
sweet flag
Szechuan lovage
Tamaricaceae
Tayuya
Terpinolene
thyme
Thymus
Trichosanthes
turmeric
Vasicine
Vasicinone
Vervain
Viola
Violet
Visnea Mocanera
vitamin C
Vladimiria souliei
Winter Savory
Wulinshen
Yellow root
Yerba buena
Yerba santa
zanthoxylum
Zedoary
Zingerone
Zingiberene
Other health conditions supported by Ligustrazin
AnginaArteriosclerosis
Arthritis
Asthma
Backache
Blood Clots (prevention of)
Bruises (healing)
Bruises (prevention)
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Chest Pain
Circulation (poor)
Circulation (to the brain)
Congestion (lungs)
Congestion (sinus)
Congestive Heart Failure
Dizziness
Edema
Eye Problems
Eyes (red or itching)
