Evidence supporting the use of: Allicin
For the health condition: Congestion (sinus)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Allicin, a bioactive compound found in garlic (Allium sativum), has been traditionally used in various cultures to help alleviate symptoms of upper respiratory congestion, including sinus congestion. The traditional use is mainly rooted in garlic’s long-standing reputation as an antimicrobial and anti-inflammatory remedy in folk medicine. For centuries, garlic preparations have been inhaled as steam or consumed orally to help "clear the sinuses" and relieve symptoms of colds and congestion.
From a scientific perspective, some studies have demonstrated allicin’s antimicrobial properties against bacteria, viruses, and fungi, which could, in theory, help address sinus infections or congestion caused by pathogens. There is also evidence that allicin can modulate inflammatory pathways, potentially reducing mucosal swelling. However, these effects have largely been demonstrated in vitro (in test tubes) or in animal models, not in robust human clinical trials specifically targeting sinus congestion. Human evidence is limited mainly to general studies on garlic’s effects on respiratory infections and immune support, with mixed results and methodological limitations.
In summary, allicin’s use for sinus congestion is primarily justified by tradition, with a moderate but not strong level of scientific plausibility based on laboratory studies. High-quality clinical trials specifically on sinus congestion are lacking, so evidence supporting its effectiveness in this context remains limited.
Other ingredients used for Congestion (sinus)
allspicealoe vera
alpha-pinene
basil
benegut perilla (proprietary)
beta-pinene
betel
black currant
black pepper
Indian frankincense
bupleurum falcatum
bасора
capsaicinoids
chamomile
chen pi
clove
Coptis chinensis
turmeric
echinacea purpurea
elderberry
fennel
forsythia
garlic bulb
ginger
onion
green tea
horseradish
licorice root
lovage
mint
mustard seed
spruce
oregano
peppermint oil
perilla
pomegranate
quercetin
rosemary
sage
shiitake mushroom
spearmint leaf
sphaeranthus indicus
thyme
vitamin C
wasabia japonica
boneset
hyssop
cardamom
atractylodes
mugwort
malabar nut
alpinia galangal
ferula assafoetida
inula racemosa
anise
blackboard tree
lemongrass
yerba santa
coltsfoot
chrysanthemum
juniper berries
sweet flag
oriental arborvitae
trichosanthes
zanthoxylum
eucalyptus
menthol oil
horehound
Sichuan pepper
cayenne pepper
sea salt
Agastache
Alpha-terpineol
Allicin
Asarum heterotropoides
Aconite
Asafoetida
Andrographolide
Adrenergic amines
Asteracea
allyl isothiocyanate
Allium tuberosum
Amor seco
Arisaema
Asarum sieboldii
Alantolactone
Atractylone
Black Seed
Baphicacanthus cusia
Bicarbonate
Balsam
Bishop's Weed
Bayleaf
Bitter Grass
Bougainvillea
Bee hive
Bioflavonoids
black salt
Bee products
Buddha's Hand
Borage
Balloon Flower
Belamcanda
Borneol
Camellia sinensis
Clerodendrum trichotomum
Coriander
Citrus
Cineole
Cajuput
Chinese Raisintree
Carvone
Cistus
Calamus
Cinnamaldehyde
Carthamus
Chondrus
Dragonhead
Ephedra
European Elder
English Horsemint
Echinacea
Elder
Ephedrine
Eugenol
Galangal
Ivy
Mustard
Sandalwood
Vervain
Other health conditions supported by Allicin
AbscessesAcne
Angina
Antibiotics (alternatives to)
Arteriosclerosis
Arthritis
Athlete's Foot
Bladder Infection
Blood Clots (prevention of)
Boils
Bronchitis
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Colds (antiviral)
Colds (general)
Colds (prevention)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Congestive Heart Failure
Cough (general)
Cough (spastic)
Cuts
Diabetes
Digestion (poor)
Dysentery
Fungal Infections
Gastritis
Giardia
Gingivitis
Glands (swollen lymph)
Gonorrhea
Headache (sinus)
Heart (weakness)
Hemorrhoids
Herpes
Hypertension
Infection
Infection (bacterial)
Inflammation
Influenza