Evidence supporting the use of: Andrographolide
For the health condition: Congestion (sinus)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Andrographolide is the main active compound found in Andrographis paniculata, an herb traditionally used in Ayurveda and Traditional Chinese Medicine. Historically, Andrographis has been used to treat a variety of respiratory ailments, including the common cold, flu, fever, and upper respiratory tract infections, which often involve symptoms like nasal congestion. Its use for sinus congestion is primarily rooted in these traditional practices, where it is believed to have anti-inflammatory, antipyretic, and immune-supportive properties. Several published clinical trials and systematic reviews suggest that standardized extracts of Andrographis paniculata may reduce the severity and duration of symptoms associated with upper respiratory tract infections, such as sore throat, cough, and nasal congestion. However, most studies focus on general respiratory infection symptom relief rather than sinus congestion specifically. While there is moderate evidence for its effectiveness in treating the common cold, the direct evidence for sinus congestion (sinusitis) is limited, and the mechanism appears to be through general immune modulation and anti-inflammatory effects rather than targeted decongestant action. Thus, the use of andrographolide for sinus congestion is supported primarily by tradition, with some emerging but not definitive scientific support.

More about andrographolide
More about Congestion (sinus)

Other ingredients used for Congestion (sinus)

Allspice
Aloe vera
alpha-pinene
basil
benegut perilla (proprietary)
beta-pinene
betel
black currant
black pepper
Indian frankincense
bupleurum falcatum
bасора
capsaicinoids
chamomile
chen pi
clove
Coptis chinensis
turmeric
echinacea purpurea
elderberry
fennel
forsythia
garlic bulb
ginger
onion
green tea
horseradish
licorice root
lovage
Mint
mustard seed
spruce
oregano
Peppermint
perilla
pomegranate
quercetin
rosemary
sage
shiitake mushroom
spearmint leaf
Sphaeranthus indicus
thyme
vitamin C
Wasabi
boneset
hyssop
cardamom
atractylodes
Mugwort
malabar nut
alpinia galangal
ferula assafoetida
inula racemosa
anise
blackboard tree
lemongrass
Yerba santa
coltsfoot
chrysanthemum
juniper berries
sweet flag
oriental arborvitae
Trichosanthes
zanthoxylum
eucalyptus
Menthol oil
horehound
Sichuan pepper
cayenne pepper
sea salt
Agastache
alpha-terpineol
Allicin
Asarum heterotropoides
Aconite
asafoetida
andrographolide
Adrenergic amines
Asteraceae
Allyl isothiocyanate
Allium tuberosum
Amor seco
Arisaema
Asarum sieboldii
Alantolactone
atractylone
black seed
Baphicacanthus cusia
bicarbonate
balsam
bishop\'s weed
bayleaf
bitter grass
Bougainvillea
bee hive
bioflavonoids
black salt
bee products
Buddha\'s hand
borage
balloon flower
Belamcanda
borneol
Camellia sinensis
Clerodendrum trichotomum
coriander
Citrus
cineole
cajuput
Chinese raisintree
carvone
Cistus
calamus
cinnamaldehyde
Carthamus
Chondrus
dragonhead
Ephedra
European Elder
English horsemint
Echinacea
Elder
ephedrine
eugenol
fang-feng
frankincense
Gnaphalium
gamma-terpinene
Gallesia
Gardenia jasminoides
Galangal
honey
Hedyotis
Houttuynia
Horsemint
Isatis
long pepper
Ivy
Ledebouriella
Litsea
Lomatium
Laggera pterodonta
limonene
Ligustrazin
labrador tea
Ligusticum
Mustard
Marjoram
Marsh Tea
Monoterpenes
Meadow sage
Mucolase
Nardostachys
Nigella seed
Nutmeg
Osha
Orris
Osmanthus
Phellodendron
Pepper
Paris polyphylla
Pyrrosia
Piper retrofractum
Piper nigrum
Rhus coriaria
ravinsara
Sabadilla
Sichuan Lovage
Sophora
Smartweed
Sesquiterpenes
Solanum indicum
Sambucus nigra
Sagebrush
Sandalwood
Scabrous Gentian
Sundew
Sassafras
Thymus
Vervain
Vasicine
Viola
Vasicinone
Wulinshen
Winter Savory
Yuzu
Yerba buena
Zedoary
Zingerone

Products containing andrographolide

We currently have no products on Vitabase that contain this ingredient.