Evidence supporting the use of: Andrographolide
For the health condition: Congestion (sinus)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Andrographolide is the main active compound found in Andrographis paniculata, an herb traditionally used in Ayurveda and Traditional Chinese Medicine. Historically, Andrographis has been used to treat a variety of respiratory ailments, including the common cold, flu, fever, and upper respiratory tract infections, which often involve symptoms like nasal congestion. Its use for sinus congestion is primarily rooted in these traditional practices, where it is believed to have anti-inflammatory, antipyretic, and immune-supportive properties. Several published clinical trials and systematic reviews suggest that standardized extracts of Andrographis paniculata may reduce the severity and duration of symptoms associated with upper respiratory tract infections, such as sore throat, cough, and nasal congestion. However, most studies focus on general respiratory infection symptom relief rather than sinus congestion specifically. While there is moderate evidence for its effectiveness in treating the common cold, the direct evidence for sinus congestion (sinusitis) is limited, and the mechanism appears to be through general immune modulation and anti-inflammatory effects rather than targeted decongestant action. Thus, the use of andrographolide for sinus congestion is supported primarily by tradition, with some emerging but not definitive scientific support.
Other ingredients used for Congestion (sinus)
AconiteAdrenergic amines
Agastache
Alantolactone
Allicin
Allium tuberosum
Allspice
Allyl isothiocyanate
Aloe vera
alpha-pinene
alpha-terpineol
alpinia galangal
Amor seco
andrographolide
anise
Arisaema
asafoetida
Asarum heterotropoides
Asarum sieboldii
Asteraceae
atractylodes
atractylone
balloon flower
balsam
Baphicacanthus cusia
basil
bayleaf
bee hive
bee products
Belamcanda
benegut perilla (proprietary)
beta-pinene
betel
bicarbonate
bioflavonoids
bishop\'s weed
bitter grass
black currant
black pepper
black salt
black seed
blackboard tree
boneset
borage
borneol
Bougainvillea
Buddha\'s hand
bupleurum falcatum
bасора
cajuput
calamus
Camellia sinensis
capsaicinoids
cardamom
Carthamus
carvone
cayenne pepper
chamomile
chen pi
Chinese raisintree
Chondrus
chrysanthemum
cineole
cinnamaldehyde
Cistus
Citrus
Clerodendrum trichotomum
clove
coltsfoot
Coptis chinensis
coriander
dragonhead
Echinacea
echinacea purpurea
Elder
elderberry
English horsemint
Ephedra
ephedrine
eucalyptus
eugenol
European Elder
fang-feng
fennel
ferula assafoetida
forsythia
frankincense
Galangal
Gallesia
gamma-terpinene
Gardenia jasminoides
garlic bulb
ginger
Gnaphalium
green tea
Hedyotis
honey
horehound
Horsemint
horseradish
Houttuynia
hyssop
Indian frankincense
inula racemosa
Isatis
Ivy
juniper berries
labrador tea
Laggera pterodonta
Ledebouriella
lemongrass
licorice root
Ligusticum
Ligustrazin
limonene
Litsea
Lomatium
long pepper
lovage
malabar nut
Marjoram
Marsh Tea
Meadow sage
Menthol oil
Mint
Monoterpenes
Mucolase
Mugwort
Mustard
mustard seed
Nardostachys
Nigella seed
Nutmeg
onion
oregano
oriental arborvitae
Orris
Osha
Osmanthus
Paris polyphylla
Pepper
Peppermint
perilla
Phellodendron
Piper nigrum
Piper retrofractum
pomegranate
Pyrrosia
quercetin
ravinsara
Rhus coriaria
rosemary
Sabadilla
sage
Sagebrush
Sambucus nigra
Sandalwood
Sassafras
Scabrous Gentian
sea salt
Sesquiterpenes
shiitake mushroom
Sichuan Lovage
Sichuan pepper
Smartweed
Solanum indicum
Sophora
spearmint leaf
Sphaeranthus indicus
spruce
Sundew
sweet flag
thyme
Thymus
Trichosanthes
turmeric
Vasicine
Vasicinone
Vervain
Viola
vitamin C
Wasabi
Winter Savory
Wulinshen
Yerba buena
Yerba santa
Yuzu
zanthoxylum
Zedoary
Zingerone
Other health conditions supported by andrographolide
AcneAntibiotics (alternatives to)
Arthritis
Asthma
Autoimmune Disorders
Boils
Bronchitis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Colitis
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Cough (general)
Cough (spastic)
Diabetes
Diarrhea
Digestion (poor)
Fever
Gastritis
Hepatitis
Herpes
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Influenza
Liver Detoxification
Malaria
Memory and Brain Function
Pain (general remedies for)
Pneumonia
Psoriasis
Rheumatoid Arthritis
Tuberculosis
Wounds and Sores
