Asarum heterotropoides, commonly known as wild ginger or "Xi Xin" in Traditional Chinese Medicine (TCM), has a long history of use for treating symptoms associated with sinus congestion, such as nasal obstruction, headache, and rhinitis. In TCM, it is described as having the properties of dispelling wind and cold, opening nasal passages, and alleviating pain. Classical texts, including the Shennong Bencao Jing and later materia medica, list its use in prescriptions for conditions resembling modern descriptions of sinusitis and upper respiratory congestion.

The active constituents of Asarum heterotropoides include volatile oils (such as methyleugenol and safrole) and aristolochic acids (the latter associated with toxicity concerns). Some pharmacological studies suggest mild anti-inflammatory, analgesic, and possibly mild decongestant effects in animal models; however, robust clinical trials in humans for sinus congestion are lacking. Safety concerns, particularly nephrotoxicity and carcinogenicity linked to aristolochic acids, have led to regulatory restrictions in some countries.

In summary, the use of Asarum heterotropoides for sinus congestion is primarily rooted in traditional practice, with limited supportive laboratory data but little substantive clinical evidence. Its use should be approached with caution due to significant safety concerns.