Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Capsaicinoids, the active compounds found in chili peppers (notably capsaicin), have some scientific evidence supporting their use in alleviating nasal and sinus congestion. The decongestant effect arises mainly from the stimulation of trigeminal nerve endings, which leads to a release of neuropeptides and results in increased mucosal secretion and vasodilation. This can provide temporary relief from nasal congestion by thinning mucus and promoting drainage. Several clinical studies have investigated intranasal capsaicin sprays for non-allergic rhinitis and have demonstrated reduced nasal symptoms and improved airflow in some patients. For example, a 2011 double-blind, placebo-controlled trial published in Annals of Allergy, Asthma & Immunology showed that capsaicin nasal spray significantly reduced nasal obstruction scores compared to placebo in patients with non-allergic rhinitis. However, the burning sensation and discomfort associated with capsaicin application can limit its acceptability for some individuals. While capsaicin’s ability to clear sinuses is more than anecdotal, its use is typically reserved for refractory cases or as a component of commercial nasal sprays rather than a first-line home remedy. The overall evidence is moderate (rated 3/5) and suggests that capsaicinoids do have a scientifically plausible and clinically observed effect on nasal congestion, though further large-scale studies are warranted to clarify optimal use and long-term safety.

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Douglas Laboratories Metabolic Lean