Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Perilla (Perilla frutescens), commonly known as shiso in East Asia, has a long history of use in traditional Chinese, Japanese, and Korean medicine. It is primarily used for its purported anti-inflammatory, anti-allergic, and expectorant properties. Traditionally, perilla leaves and seeds have been used to help relieve symptoms of respiratory issues, including nasal congestion, sinusitis, and coughs. In traditional Chinese medicine (TCM), perilla is classified as a herb that can "release the exterior," meaning it is used to treat symptoms of the common cold, such as stuffy nose and congestion, especially when associated with wind-cold invasion.

Modern scientific evidence supporting the use of perilla for sinus congestion is limited but suggests some potential mechanisms. Perilla contains bioactive compounds such as rosmarinic acid, luteolin, and apigenin, which have demonstrated anti-inflammatory and anti-allergic effects in laboratory studies. These properties could theoretically help reduce nasal inflammation and congestion. Some small animal studies and in vitro experiments have shown that perilla extracts can inhibit the release of histamine and other inflammatory mediators, which may alleviate symptoms associated with allergic rhinitis and sinus congestion. However, large-scale clinical trials in humans are lacking, and most evidence remains preliminary.

In conclusion, the use of perilla for congestion is primarily based on traditional practices, with only modest scientific support for its effectiveness. Further research is needed to validate its efficacy in treating sinus congestion in humans.

More about perilla
More about Congestion (sinus)

Other ingredients used for Congestion (sinus)

Other health conditions supported by perilla

Products containing perilla

Metagenics Echinacea Synergy
Designs For Health IBSynergy™
Pure Encapsulations Perilla Extract
Metagenics Perimine®
Pure Encapsulations Th2 Modulator