Evidence supporting the use of: Arjunic acid
For the health condition: Congestive Heart Failure
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Arjunic Acid is a triterpenoid compound isolated from the bark of Terminalia arjuna, a tree long used in Ayurvedic medicine for cardiovascular health. The traditional use of Terminalia arjuna bark for heart conditions, including congestive heart failure (CHF), is well documented in historical Ayurvedic texts. In terms of scientific validation, some preclinical and limited clinical studies have investigated the effects of Arjunic Acid and Terminalia arjuna extracts on heart function.
Animal studies suggest that Arjunic Acid possesses antioxidant, anti-inflammatory, and cardioprotective properties, potentially beneficial in CHF. These effects are thought to involve improved myocardial contractility, reduced oxidative stress, and modulation of lipid levels. Some small-scale human studies and clinical trials using Terminalia arjuna bark extract (which contains Arjunic Acid among other compounds) have shown improvements in symptoms and cardiac function in CHF patients. However, these studies are limited by small sample sizes, short durations, lack of standardization of extracts, and a focus on the whole bark rather than isolated Arjunic Acid.
Overall, while there is promising preliminary evidence and a strong tradition of use, robust clinical trials specifically targeting isolated Arjunic Acid in CHF are lacking. Thus, scientific support exists but is currently weak to moderate and should be considered preliminary.
Other ingredients used for Congestive Heart Failure
adenosine 5-triphosphate disodium (ATP)algal oil
Allicin
AMP-activated protein kinase (AMPK)
Arginine orotate
arjun tree
arjuna
arjunic acid
astragaloside
astragalus
black garlic
black seed
catecholamine
Chinese silkvine
coenzyme Q10 (CoQ10)
cowherb
danshen
DHA (docosahexaenoic acid)
Digitalis
docosahexaenoic Acid
DPA (docosapentaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
fatty acids
fish oil
flavanols
flavonols
foxglove
garlic bulb
ginseng
Glycoside
hawthorn
L-arginine
l-carnitine
L-citrulline
L-taurine
Ligustrazin
Marine lipid
Monounsaturated fat
N-acetyl-cysteine (NAC)
nicotinamide riboside
Nigella seed
omega-3 fatty acids
Ophiopogon
ophiopogon root
Osthole
Phosphocreatine
Phthalides
polyunsaturated fat
potassium
Propionyl-L-Carnitine
Puerarin
resveratrol
ribose
Salmon Oil
Salvianolic acid
Tanshinone
Taurine
Theophylline
Thiamin (vitamin B1)
ubiquinol
vitamin D
Zinc
β-nicotinamide mononucleotide (NMN)
