Evidence supporting the use of: Hawthorn
For the health condition: Congestive Heart Failure
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Hawthorn (Crataegus spp.) has a long history of use in traditional European herbal medicine for various cardiovascular conditions, including congestive heart failure (CHF). In recent decades, its use has received growing scientific scrutiny. Several randomized, placebo-controlled clinical trials and meta-analyses have investigated standardized hawthorn leaf and flower extracts (notably WS 1442 and LI 132) as adjunctive therapy for mild to moderate CHF (New York Heart Association class II–III). These studies have generally shown that hawthorn can produce modest improvements in symptoms such as fatigue and shortness of breath, as well as in exercise tolerance and certain cardiac parameters (e.g., left ventricular ejection fraction). Proposed mechanisms of action include positive inotropic effects, vasodilation, antioxidant properties, and improvement of coronary blood flow.
A 2008 Cochrane review concluded that hawthorn extracts offered "significant benefit in symptom control and physiologic outcomes" when used alongside conventional therapy, though the clinical significance of these changes was debated, and most studies were of short duration (8–16 weeks). Importantly, hawthorn is not a replacement for standard CHF therapies and is best considered as a complementary option. Adverse effects appear uncommon and mild, but caution is advised regarding potential interactions with cardiac medications.
Overall, there is moderate scientific validation supporting the adjunctive use of hawthorn in mild to moderate CHF, justifying a rating of 3 out of 5 for evidence. Its use is not supported for severe CHF or as monotherapy.
Other ingredients used for Congestive Heart Failure
adenosine 5-triphosphate disodium (ATP)algal oil
Allicin
AMP-activated protein kinase (AMPK)
Arginine orotate
arjun tree
arjuna
arjunic acid
astragaloside
astragalus
black garlic
black seed
catecholamine
Chinese silkvine
coenzyme Q10 (CoQ10)
cowherb
danshen
DHA (docosahexaenoic acid)
Digitalis
docosahexaenoic Acid
DPA (docosapentaenoic acid)
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
fatty acids
fish oil
flavanols
flavonols
foxglove
garlic bulb
ginseng
Glycoside
hawthorn
L-arginine
l-carnitine
L-citrulline
L-taurine
Ligustrazin
Marine lipid
Monounsaturated fat
N-acetyl-cysteine (NAC)
nicotinamide riboside
Nigella seed
omega-3 fatty acids
Ophiopogon
ophiopogon root
Osthole
Phosphocreatine
Phthalides
polyunsaturated fat
potassium
Propionyl-L-Carnitine
Puerarin
resveratrol
ribose
Salmon Oil
Salvianolic acid
Tanshinone
Taurine
Theophylline
Thiamin (vitamin B1)
ubiquinol
vitamin D
Zinc
β-nicotinamide mononucleotide (NMN)
Other health conditions supported by hawthorn
Abdominal PainAngina
Arrhythmia
Arteriosclerosis
Cardiovascular Disease
Chest Pain
Cholesterol (high)
Circulation (poor)
Cold Hands and Feet
Congestive Heart Failure
Edema
Heart (weakness)
Heart Fibrillation or Palpitations
Heart Valves
Hypertension
Mitral Valve
Triglycerides (high)
Products containing hawthorn
Vitabase
Blood Pressure Support
Metagenics
Cardiogenics® Intensive Care
Pure Encapsulations
Hawthorn Extract
Douglas Laboratories
Hawthorne Max-V
Thorne
Heart Health Complex Q-10 Plus
Pure Encapsulations
Ultra Pure Pack
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
Vascular Relax
