Evidence supporting the use of: Hawthorn
For the health condition: Congestive Heart Failure
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Hawthorn (Crataegus spp.) has a long history of use in traditional European herbal medicine for various cardiovascular conditions, including congestive heart failure (CHF). In recent decades, its use has received growing scientific scrutiny. Several randomized, placebo-controlled clinical trials and meta-analyses have investigated standardized hawthorn leaf and flower extracts (notably WS 1442 and LI 132) as adjunctive therapy for mild to moderate CHF (New York Heart Association class II–III). These studies have generally shown that hawthorn can produce modest improvements in symptoms such as fatigue and shortness of breath, as well as in exercise tolerance and certain cardiac parameters (e.g., left ventricular ejection fraction). Proposed mechanisms of action include positive inotropic effects, vasodilation, antioxidant properties, and improvement of coronary blood flow.
A 2008 Cochrane review concluded that hawthorn extracts offered "significant benefit in symptom control and physiologic outcomes" when used alongside conventional therapy, though the clinical significance of these changes was debated, and most studies were of short duration (8–16 weeks). Importantly, hawthorn is not a replacement for standard CHF therapies and is best considered as a complementary option. Adverse effects appear uncommon and mild, but caution is advised regarding potential interactions with cardiac medications.
Overall, there is moderate scientific validation supporting the adjunctive use of hawthorn in mild to moderate CHF, justifying a rating of 3 out of 5 for evidence. Its use is not supported for severe CHF or as monotherapy.
Other ingredients used for Congestive Heart Failure
adenosine 5-triphosphate disodium (ATP)algal oil
arjun tree
astragalus
black garlic
coenzyme Q10 (CoQ10)
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
garlic bulb
ginseng
hawthorn
l-arginine
l-carnitine
l-citrulline
l-taurine
marine lipid
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
ophiopogon root
potassium
resveratrol
thiamin (vitamin B1)
ubiquinol
vitamin D
zinc
β-nicotinamide mononucleotide (NMN)
AMP-activated protein kinase (AMPK)
Arjuna
Allicin
Arginine orotate
Astragaloside
Arjunic Acid
Black Seed
Chinese Silkvine
Catecholamine
Cowherb
Docosahexaenoic Acid
Danshen
Digitalis
Eicosapentaenoic Acid
Theophylline
Other health conditions supported by hawthorn
Abdominal PainAngina
Arrhythmia
Arteriosclerosis
Cardiovascular Disease
Chest Pain
Cholesterol (high)
Circulation (poor)
Cold Hands and Feet
Congestive Heart Failure
Edema
Heart (weakness)
Heart Fibrillation or Palpitations
Heart Valves
Hypertension
Mitral Valve
Triglycerides (high)
Products containing hawthorn
Vitabase
Blood Pressure Support
Metagenics
Cardiogenics® Intensive Care
Pure Encapsulations
Hawthorn Extract
Douglas Laboratories
Hawthorne Max-V
Thorne
Heart Health Complex Q-10 Plus
Pure Encapsulations
Ultra Pure Pack
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
Vascular Relax