Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ophiopogon root (Ophiopogon japonicus, known as Mai Men Dong in Traditional Chinese Medicine) has a long-standing history of use in Chinese herbal medicine, especially for conditions described as "yin deficiency" and to "nourish the heart." In classical and modern herbal compendiums, ophiopogon root is often included in formulas for cardiovascular symptoms such as palpitations, chest tightness, and shortness of breath, which are sometimes interpreted in modern contexts as manifestations of heart failure or related conditions. However, this use is grounded primarily in traditional theory and clinical experience rather than robust scientific validation.

There is limited scientific research specifically evaluating ophiopogon root for congestive heart failure (CHF). Most available studies are either in vitro or animal studies focusing on potential cardioprotective effects, such as anti-inflammatory, antioxidant, or anti-apoptotic actions. A few small clinical studies in China have investigated herbal formulas containing ophiopogon root for heart failure, but these studies often lack rigorous controls, have small sample sizes, and combine multiple herbs, making it difficult to attribute effects to ophiopogon alone.

In summary, while ophiopogon root is traditionally used to support heart function in Chinese medicine, and there is some preclinical rationale for its effects, the evidence supporting its use in CHF is weak and mostly traditional, not scientific. Well-designed clinical trials are lacking, so its role in treating or supporting congestive heart failure remains unproven by current scientific standards.

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