Evidence supporting the use of: Safflower
For the health condition: Congestive Heart Failure
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Safflower (Carthamus tinctorius) has a long history of use in traditional Chinese medicine and other herbal systems for cardiovascular health, including conditions that resemble what is now classified as congestive heart failure (CHF). Traditionally, safflower is said to "invigorate the blood" and "remove blood stasis," and its flowers are used in formulas intended to improve circulation and address symptoms like chest pain and palpitations. In Chinese medicine, it is often combined with other herbs for these purposes.
Scientific evidence supporting safflower’s use specifically for congestive heart failure is limited. Some small studies and animal experiments suggest that safflower extracts may have vasodilatory, anti-inflammatory, and antithrombotic effects, which could potentially benefit cardiovascular function. However, these studies often use isolated compounds or high doses not reflective of typical supplemental use. There are no large, high-quality clinical trials directly demonstrating efficacy in CHF patients. Thus, while traditional use for "heart-related" symptoms is well documented, robust scientific validation—especially for modern CHF diagnosis and management—is lacking.
In summary, the use of safflower for congestive heart failure is primarily rooted in traditional medicine, with only limited and indirect scientific support. It should not replace evidence-based medical therapies for CHF.
Other ingredients used for Congestive Heart Failure
adenosine 5-triphosphate disodium (ATP)algal oil
arjun tree
astragalus
black garlic
coenzyme Q10 (CoQ10)
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
garlic bulb
ginseng
hawthorn
l-arginine
l-carnitine
l-citrulline
l-taurine
marine lipid
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
ophiopogon root
potassium
resveratrol
thiamin (vitamin B1)
ubiquinol
vitamin D
zinc
β-nicotinamide mononucleotide (NMN)
AMP-activated protein kinase (AMPK)
Arjuna
Allicin
Arginine orotate
Astragaloside
Arjunic Acid
Black Seed
Chinese Silkvine
Catecholamine
Cowherb
Docosahexaenoic Acid
Danshen
Digitalis
Eicosapentaenoic Acid
Theophylline
Other health conditions supported by Safflower
Abdominal PainAngina
Arthritis
Blood Clots (prevention of)
Bruises (healing)
Bruises (prevention)
Cancer (natural therapy for)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Congestion (bronchial)
Congestive Heart Failure
Constipation (adults)
Constipation (children)
Cough (general)
Cough (spastic)
Diabetes
Digestion (poor)
Edema
Fatty Liver Disease
Gastritis
Hypertension
Inflammation
Insomnia
Liver Detoxification
Migraine
Pain (general remedies for)
Phlebitis
Rheumatoid Arthritis
Triglycerides (high)
Varicose Veins
Wounds and Sores