Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sphaeranthus indicus, commonly known as East Indian globe thistle, has a longstanding role in various traditional medicine systems, particularly Ayurveda and Unani, for the management of eye diseases including conjunctivitis. Traditional uses are documented in classical Ayurvedic texts, where the plant is employed for its purported anti-inflammatory, antimicrobial, and soothing properties. The flowers and leaves are sometimes used in the form of decoctions or pastes applied topically to the eyes, or as washes to alleviate redness, discharge, and irritation associated with conjunctivitis.

However, direct scientific evidence supporting the efficacy of Sphaeranthus indicus specifically for conjunctivitis is limited. A few in vitro and animal studies suggest that extracts of the plant possess antimicrobial and anti-inflammatory activities, which could theoretically be beneficial in treating conjunctivitis, a condition often caused by bacterial or viral infections and characterized by inflammation. For example, some studies have demonstrated inhibitory effects of Sphaeranthus indicus extracts against common pathogens and reduction of inflammation in animal models. However, these findings are not directly linked to clinical studies on conjunctivitis in humans.

In summary, the use of Sphaeranthus indicus for conjunctivitis is primarily based on traditional practices rather than robust clinical evidence. The traditional claims are partially supported by preliminary pharmacological studies, but high-quality, targeted clinical research is lacking.

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