Bio Ecolian (proprietary) is a branded form of α-glucan oligosaccharides (sometimes called α-glucooligosaccharides), which are classified as prebiotics. Prebiotics are non-digestible food ingredients that beneficially affect the host by selectively stimulating the growth and/or activity of beneficial bacteria in the colon. The rationale for using Bio Ecolian in the support or treatment of adult constipation is based primarily on its demonstrated prebiotic effects, which can improve stool frequency and consistency by enhancing the health and activity of the gut microbiome.

Clinical studies on prebiotics such as inulin, fructooligosaccharides, and, more recently, α-glucan oligosaccharides, have shown improvement in bowel movement frequency and relief of constipation symptoms in adults. While studies specifically on the proprietary Bio Ecolian formulation are limited, research on structurally similar α-glucan oligosaccharides has shown that they can increase fecal bulk and water content, likely through increased short-chain fatty acid production and changes in microbiota composition favoring bifidobacteria and lactobacilli.

The European Food Safety Authority (EFSA) recognizes certain prebiotics for their role in normal bowel function, though claims for specific brands like Bio Ecolian require more direct evidence. Therefore, while the use of Bio Ecolian for adult constipation is supported by general scientific principles and studies on related compounds, direct clinical trial data specific to Bio Ecolian are still emerging. The current evidence level is moderate, warranting a rating of 3 out of 5.