Evidence supporting the use of: Cape aloe
For the health condition: Constipation (adults)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Cape Aloe (Aloe ferox) is used to treat constipation primarily due to its well-established laxative properties. The dried latex of Cape Aloe contains anthraquinone glycosides (such as aloin), which are metabolized in the colon by bacteria to active compounds that stimulate peristalsis and increase water secretion in the bowel, resulting in a laxative effect. This mechanism is similar to that of senna and cascara sagrada, other well-known stimulant laxatives.

There is scientific validation for the use of Cape Aloe in treating constipation in adults. Multiple in vitro and animal studies, as well as some human clinical trials, have demonstrated its efficacy as a short-term remedy for occasional constipation. For instance, a randomized controlled trial comparing Aloe, cascara, and psyllium in adults with chronic constipation found that Aloe was effective at increasing stool frequency and softening stool consistency. However, the number of high-quality, large-scale human trials is limited, and most evidence comes from traditional use, case reports, and small studies.

Regulatory agencies such as the European Medicines Agency (EMA) recognize the use of Aloe latex preparations for short-term relief of occasional constipation but caution against long-term use due to the risk of adverse effects, such as electrolyte imbalances and dependence. In summary, there is scientific evidence supporting its short-term use for constipation, though safety concerns warrant caution.

More about cape aloe
More about Constipation (adults)

Other ingredients used for Constipation (adults)

Acacia
Actinidin
Aerva lanata
Agar
Agastache
Alexandrian senna
Algae
Allium tuberosum
Almond fruit
Aloe vera
Aloin
alpinia galangal
Amomum
Amor seco
Angelica
anise
anthraquinone
apple
apple cider vinegar
apricot
arabinoxylan
Ardisia
Asam gelugor
asparagus
aster root
Asteraceae
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avocado
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bee products
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butternut
butyric acid
bасора
cabbage
cactus
Caesalpinia crista
California chia
cantaloupe
cape aloe
caraway
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Carthamus
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cascaroside
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galactooligosaccharides
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guar gum
Guava
gum
Helicteres isora
hemicellulose
honey
hyacinth bean
hydroxyanthracene derivatives
Hygrophila
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inulin
isomalto-oligosaccharide
Jalap
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oat
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vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
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Wulinshen
xylooligosaccharides
Yacon
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Yerba buena
zanthoxylum
Zedoary
Zingerone
Zucchini

Products containing cape aloe

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