Evidence supporting the use of: Lactobacillus (mixed)
For the health condition: Constipation (adults)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus (mixed strains) has been investigated for its potential to support or treat constipation in adults, with a moderate amount of scientific evidence. Several randomized controlled trials and meta-analyses suggest that certain probiotic mixtures, including various Lactobacillus species, may improve bowel movement frequency and stool consistency in adults with constipation. However, the evidence is inconsistent, and benefits appear to vary depending on the specific strains used, dosage, and study populations.

A 2017 meta-analysis published in Alimentary Pharmacology & Therapeutics reviewed 21 studies and found that probiotics, including Lactobacillus strains, increased stool frequency by an average of 0.99 bowel movements per week compared to placebo. However, the effect sizes were modest, and not all studies demonstrated significant improvements. Another 2020 systematic review in Clinical Nutrition concluded that probiotics may have a small beneficial effect, particularly in cases of functional constipation, but emphasized the heterogeneity of available studies.

Most guidelines do not yet recommend probiotics, including mixed Lactobacillus, as standard therapy for constipation due to limited high-quality evidence and lack of consensus on optimal strains and formulations. In summary, while there is some scientific validation for the use of mixed Lactobacillus in constipation, the evidence is not robust, and effects are likely modest and strain-specific.

More about Lactobacillus (mixed)
More about Constipation (adults)

Other ingredients used for Constipation (adults)

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mannitol
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Products containing Lactobacillus (mixed)

We currently have no products on Vitabase that contain this ingredient.