Evidence supporting the use of: Lactobacillus (mixed)
For the health condition: Constipation (adults)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Lactobacillus (mixed strains) has been investigated for its potential to support or treat constipation in adults, with a moderate amount of scientific evidence. Several randomized controlled trials and meta-analyses suggest that certain probiotic mixtures, including various Lactobacillus species, may improve bowel movement frequency and stool consistency in adults with constipation. However, the evidence is inconsistent, and benefits appear to vary depending on the specific strains used, dosage, and study populations.
A 2017 meta-analysis published in Alimentary Pharmacology & Therapeutics reviewed 21 studies and found that probiotics, including Lactobacillus strains, increased stool frequency by an average of 0.99 bowel movements per week compared to placebo. However, the effect sizes were modest, and not all studies demonstrated significant improvements. Another 2020 systematic review in Clinical Nutrition concluded that probiotics may have a small beneficial effect, particularly in cases of functional constipation, but emphasized the heterogeneity of available studies.
Most guidelines do not yet recommend probiotics, including mixed Lactobacillus, as standard therapy for constipation due to limited high-quality evidence and lack of consensus on optimal strains and formulations. In summary, while there is some scientific validation for the use of mixed Lactobacillus in constipation, the evidence is not robust, and effects are likely modest and strain-specific.
More about Lactobacillus (mixed)
More about Constipation (adults)
Other ingredients used for Constipation (adults)
aloe veraapple
apricot
asparagus
bacillus coagulans
bacillus subtilis
barley
basil
beet
myrobalan
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bio ecolian (proprietary)
black cumin
black currant
black pepper
radish
blackberry
broccoli
bupleurum falcatum
burdock
bасора
carrot
cauliflower
celery
chamomile
chia seed
chicory
chlorella
cinnamon
clove
coconut milk
cowage seed
cucumber
turmeric
d-sorbitol
dandelion
dog rose
melon
fennel
fiber blend (proprietary)
flaxseed
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
ginger
ginseng
gooseberry
green banana
onion
green tea
greens blend (proprietary)
guar gum
cellulose
Indian gum arabic tree
Indian tinospora
inulin
isomalto-oligosaccharide
jujube
kale
kudzu
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lemon
licorice root
lovage
magnesium
mango
mannitol
moringa
nettle
oat
ophiopogon root
orange
parsley
pear
pectin
perilla
pineapple
plantain
plum fruit
pomegranate
potato starch
prebiotic blend (proprietary)
butyric acid
prune
psyllium
pumpkin
quail egg
raspberry
redcurrant
rhizome
rhubarb root
slippery elm bark
sorbitol
sphaeranthus indicus
spinach
streptococcus thermophilus
thyme
tomato
triphala
almond fruit
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
seaweed
watercress
watermelon
xylooligosaccharides
cascara sagrada
tangerine
cardamom
atractylodes
papaya
mugwort
Indian bael
neem tree
nut grass
alpinia galangal
anise
punarnava
tinospora cordifolia
caesalpinia crista
swertia
peony
lingusticum wallichii
morus
lemongrass
sunflower
root tuber
flowering quince
dioscorea
ganoderma
sweet flag
hyacinth bean
morinda
trichosanthes
zanthoxylum
polyphenols
caraway
purslane
senna
aster root
peach
noni
nopal
goji berry
paw paw
millet seed
algae
indigo leaves
enzymes blend (proprietary)
cayenne pepper
soursop
sea salt
Agar
Apple Cider Vinegar
Actinidin
Agastache
Anthraquinone
Ardisia
Angelica
acacia
Auricularia
Amomum
Avocado
Alexandrian senna
Aloin
Aerva lanata
Asam gelugor
Asteracea
Arabinoxylan
Allium tuberosum
Amor seco
Atractylone
Black Seed
Bifidobacterium
Buttermilk
Bifidobacterium adolescentis
Baliospermum
Bidens pilosa
Broussonetia
Brassica
Bishop's Weed
Belleric myrobalan
Bran
Butea monosperma
Bitter Grass
Bael
Bean
Butternut
Baccharoides anthelmintica
black salt
Bifidobacterium animalis
Bee products
Bombax
Borassus Palm
Borassus aethiopum
Bitter principals
Bacteria
banana
Baobab
Bifidobacteria
Bacillus
Bassia scoparia
Boerhavia diffusa
Bottle gourd
Borneol
Cumin
Coconut
Chinese Silkvine
Curry leaf
California chia
Cinnamomum
Cascaroside
Cucurbita
coconut oil
Coriander
Cactus
Cynomorium
Cape Aloe
Citrus
Cantaloupe
Cereal grass
Chinese Raisintree
Cruciferous
Cyclanthera pedata
Curcumen
Chard
Chenopodium
Curcuma
Cabbage
Chirata
Clostridium butyricum
Castor Oil
Carthamus
Colocynth
Celosia
Currant
Chondrus
Dianthus
Dextrin
Dragonhead
Dianthrone
Dwarf Morning Glory
Date
Dulse
Emblicanin
Endive
Embelia
Emodin
Fig
Fiber
Flavonoids
Galangal
Lotus
Molasses
Phosphate Salt
Prickly Pear Cactus
Quince
Rose
Rhubarb
Sumac
Vinegar
Wheat
Zucchini
Other health conditions supported by Lactobacillus (mixed)
Acid IndigestionAntibiotics (side effects of)
Anxiety
Bladder Infection
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Colitis
Constipation (adults)
Constipation (children)
Diarrhea
Digestion (poor)
Diverticulitis
Gastritis
Irritable Bowel Syndrome
Lactose Intolerance
Leaky Gut Syndrome
Oral Surgery
Small Intestinal Bacterial Overgrowth
Thrush
Ulcers
Urinary Tract Infections
Vaginitis
Wounds and Sores