Evidence supporting the use of: Manna
For the health condition: Constipation (adults)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Manna, a sweet exudate from the bark of certain Fraxinus species (such as Fraxinus ornus), has a long history of use as a mild laxative in traditional European and Middle Eastern medicine. Its use for the treatment of constipation, particularly in adults and children, is documented in historical pharmacopeias and herbal texts. The main active component, mannitol, is a sugar alcohol that has osmotic laxative properties, drawing water into the intestines to stimulate bowel movements.

While traditional use is well established, scientific validation is limited. Some small-scale studies and pharmacological research have confirmed that mannitol and other sugars present in manna can have a laxative effect, similar to other osmotic laxatives like lactulose or sorbitol. However, these studies are few, often outdated, and not of high methodological quality. Modern clinical trials specifically evaluating manna as a treatment for constipation in adults are lacking.

In summary, the use of manna for constipation is primarily justified by tradition and some pharmacological rationale based on its osmotic effects, but robust scientific evidence (such as large randomized controlled trials) is lacking. As such, it is rated as a 2 on the evidence scale, indicating that it is supported by traditional use and limited scientific rationale, but not by strong clinical data.

More about Manna
More about Constipation (adults)

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Products containing Manna

We currently have no products on Vitabase that contain this ingredient.