Evidence supporting the use of: Mannanoligosaccharides
For the health condition: Constipation (adults)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Mannanoligosaccharides (MOS) are prebiotic fibers derived from the cell walls of yeast (Saccharomyces cerevisiae) and are primarily studied for their effects on gut health. There is a modest body of scientific evidence suggesting that MOS may have beneficial effects on bowel function, including the alleviation of constipation in adults. Prebiotics such as MOS can stimulate the growth of beneficial gut bacteria, particularly bifidobacteria and lactobacilli. These bacteria produce short-chain fatty acids (SCFAs) through fermentation, which can increase stool bulk and promote regular bowel movements.
However, the evidence specifically for MOS in adult constipation is limited and less robust compared to other prebiotics like inulin or fructooligosaccharides. Most studies focus on animal models, and those involving humans are often small-scale or conducted in specialized populations (such as the elderly or those with specific gastrointestinal conditions). Some small clinical trials and observational studies have reported improvements in stool frequency and consistency with MOS supplementation, but larger, high-quality randomized controlled trials are lacking.
In summary, while the mechanism of action for MOS as a prebiotic suggests a plausible benefit for constipation, and there are some supportive findings, the overall quality and quantity of evidence specifically for adult constipation is modest. Therefore, MOS can be considered a scientifically plausible but not strongly validated option for supporting bowel regularity in adults.
More about Mannanoligosaccharides
More about Constipation (adults)
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Other health conditions supported by Mannanoligosaccharides
Antibiotics (alternatives to)Antibiotics (side effects of)
Cholesterol (high)
Colitis
Constipation (adults)
Constipation (children)
Diarrhea
Digestion (poor)
Enteritis
Infection
Infection (bacterial)
Inflammation
Inflammatory Bowel Disorders
Irritable Bowel Syndrome
Leaky Gut Syndrome
Metabolic Syndrome
Small Intestinal Bacterial Overgrowth