Relationship: Constipation (adults) and Sodium Phosphate

Evidence supporting the use of: Sodium Phosphate
For the health condition: Constipation (adults)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Sodium phosphate is scientifically validated for the treatment of constipation, particularly in adults. It is commonly used in the form of oral solutions or rectal enemas (such as Fleet® enemas) as an osmotic laxative. The mechanism involves the attraction of water into the intestinal lumen, which increases stool volume and stimulates peristalsis, thereby promoting bowel evacuation. Clinical guidelines and authoritative sources, including the U.S. Food and Drug Administration (FDA) and gastroenterology societies, recognize sodium phosphate preparations for acute bowel cleansing prior to procedures (such as colonoscopy) as well as for relief of occasional constipation. Multiple randomized controlled trials and systematic reviews support its efficacy and rapid onset of action when compared to other laxatives. However, sodium phosphate must be used with caution, as improper dosing or use in susceptible populations (such as those with kidney dysfunction, the elderly, or those on certain medications) can cause serious side effects, including electrolyte imbalances (hyperphosphatemia, hypocalcemia, hypernatremia), dehydration, and in rare cases, acute phosphate nephropathy. Thus, its use is generally recommended for short-term, occasional relief of constipation rather than chronic management. In summary, sodium phosphate has robust scientific support (evidence level 5/5) for use in the short-term treatment of constipation in adults, provided that attention is paid to proper dosing and contraindications to minimize the risk of adverse effects.

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Evidence supporting the use of: Sodium Phosphate
For the health condition: Constipation (adults)

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Synopsis

Other ingredients used for Constipation (adults)

Other health conditions supported by Sodium Phosphate

Products containing Sodium Phosphate

Health Concerns

Brands

Evidence supporting the use of: Sodium PhosphateFor the health condition: Constipation (adults)

Table of Contents

Synopsis

Other ingredients used for Constipation (adults)

Other health conditions supported by Sodium Phosphate

Products containing Sodium Phosphate

Evidence supporting the use of: Sodium Phosphate
For the health condition: Constipation (adults)