Evidence supporting the use of: Alexandrian senna
For the health condition: Constipation (children)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Alexandrian senna (Cassia senna or Senna alexandrina) is widely used as a stimulant laxative for the treatment of constipation, including in pediatric populations. Its primary active components, sennosides, act by stimulating peristalsis and altering electrolyte transport in the colon, which promotes bowel movement. The use of senna for constipation is supported by both historical use and modern clinical studies.
Several clinical guidelines, such as those from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN), include senna as an option for treating pediatric constipation, especially in cases where osmotic laxatives like polyethylene glycol are ineffective or not tolerated. Systematic reviews and randomized controlled trials have found that senna is effective and generally safe for short-term use in children, although side effects like abdominal cramping and diarrhea can occur.
However, it is generally recommended that senna should not be used for prolonged periods in children due to potential risks such as dependence, electrolyte imbalance, and possible damage to the colonic mucosa. The quality of evidence for short-term use is moderate to high, but there is less data on long-term safety. In summary, the use of Alexandrian senna for pediatric constipation is scientifically validated for short-term management, supported by clinical evidence and guideline recommendations.
More about Alexandrian senna
More about Constipation (children)
Other ingredients used for Constipation (children)
2'-FucosyllactoseAgar
Alexandrian senna
Allium tuberosum
Almond fruit
Aloe vera
Aloin
alpinia galangal
Amomum
Amor seco
anise
anthraquinone
apple
Appleblossom Cassia
apricot
arabinoxylan
Ardisia
Asam gelugor
Asteraceae
atractylodes
atractylone
Bacillus
bacillus coagulans
bacteria
bael
bamboo
basil
Bassia scoparia
bee products
beet
belleric myrobalan
Bidens pilosa
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bio ecolian (proprietary)
bishop\'s weed
bitter grass
black salt
black seed
blackberry
blackboard tree
blueberry
Bombax
borassus palm
borneol
bottle gourd
bran
Broussonetia
butternut
bасора
cabbage
cactus
cantaloupe
carrot
cascara sagrada
cascaroside
castor oil
Celosia
chamomile
Chenopodium
chicory
chirata
Chondrus
cinnamon
Citrus
citrus sinensis (proprietary)
Clostridium butyricum
coconut
coconut milk
Coptis chinensis
cowage seed
cucumber
Curcuma
currant
curry leaf
Cyclanthera pedata
Cynomorium
date
dianthrone
dioscorea
dodder
Eclipta
fennel
fiber
fiber blend (proprietary)
fig
Frangula
fructan
fructooligosaccharides (FOS)
fruit
fruit and vegetable blend (proprietary)
galactomannan
galactooligosaccharides
Galangal
Glucofrangulin
grape
green banana
guar gum
Guava
honey
hydroxyanthracene derivatives
Hydroxycellulose
Hygrophila
Indian bael
Indian kinotree
Indian tinospora
indigo leaves
inulin
isomalto-oligosaccharide
Jalap
jujube
jungli-bean
karaya gum
Kefir
lactitol
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus gasseri
Lactobacillus kefiri
Lactobacillus pentosus
Lactobacillus reuteri
Lactococcus rhamnosus
lemon
ligustilides
lodhtree
long pepper
luffa
Methylcellulose
Moringa
Mucilage
Mugwort
Myrobalan
Nettle
nut grass
Nutmeg
Nymphaea nouchali
Oligosaccharides
Operculina turpethum
Ophiopogon
orange
Oryza sativa
Osmanthus
Palmyra
papaya
peach
pear
Phaeophyceae
phellodendron amurense
Phyllanthus
pineapple
Piper nigrum
Piper retrofractum
Plantago
plum fruit
Polygonum
polyphenols
polysaccharides
pomegranate
prebiotic blend (proprietary)
probiotics
prune
psyllium
pumpkin
punarnava
Pyrrosia
raspberry
Rhamnus nakaharai
rhizome
rhubarb
ricinoleic acid
root tuber
Rubiaceae
seaweed
senna
Sennosides
Sesbania
Sete sangrias
Sicklepod
Slippery Elm
slippery elm bark
Solanum indicum
soursop
spinach
squawvine
streptococcus thermophilus
Sulfated polysaccharide
sweet flag
Tamaricaceae
Tamarind
Tea
Triphala
turmeric
vegetable and fruit blend (proprietary)
Watermelon
Wax Gourd
Wheat
Yacon
Yerba buena
Zedoary
Zingerone
Zucchini
Other health conditions supported by Alexandrian senna
Colon (atonic)Colon (spastic)
Constipation (adults)
Constipation (children)
Digestion (poor)
Irritable Bowel Syndrome