Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Hydroxyanthracene derivatives, such as those found in senna, cascara, and aloe, have a long history of use as stimulant laxatives to treat constipation. Their application in adults is well documented in traditional medicine practices, and some regulatory authorities have recognized their short-term use in adults. However, the use of hydroxyanthracene derivatives in children is supported primarily by tradition rather than robust scientific evidence. Historical texts and pharmacopeias note their occasional use for pediatric constipation, but clinical studies specifically evaluating safety and efficacy in children are lacking or of low quality. Safety concerns, such as the risk of cramping, dehydration, and potential for misuse, have led to caution or contraindication in pediatric populations in many modern guidelines. Regulatory agencies such as the European Medicines Agency (EMA) advise against their use in children under 12 years. Thus, while these compounds have historical precedent as remedies for constipation in children, current evidence from controlled studies is insufficient to support their safety and efficacy in this population, and traditional use is the main justification for their application in pediatric constipation.

More about hydroxyanthracene derivatives
More about Constipation (children)

Other ingredients used for Constipation (children)

2'-Fucosyllactose
aloe vera
apple
apricot
bacillus coagulans
bamboo
basil
beet
myrobalan
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bio ecolian (proprietary)
blackberry
blueberry
bасора
carrot
chamomile
chicory
cinnamon
citrus sinensis (proprietary)
coconut milk
Coptis chinensis
cowage seed
cucumber
turmeric
d-sorbitol
fennel
fiber blend (proprietary)
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
grape
green banana
guar gum
cellulose
Indian tinospora
inulin
isomalto-oligosaccharide
jujube
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus gasseri
lactobacillus reuteri
lemon
mannitol
moringa
nettle
orange
pear
phellodendron amurense
pineapple
plum fruit
pomegranate
potato starch
prebiotic blend (proprietary)
prune
psyllium
pumpkin
raspberry
rhizome
slippery elm bark
sorbitol
spinach
streptococcus thermophilus
tomato
triphala
almond fruit
vegetable and fruit blend (proprietary)
seaweed
watermelon
squawvine
cascara sagrada
tangerine
atractylodes
papaya
mugwort
Indian bael
nut grass
alpinia galangal
anise
punarnava
blackboard tree
root tuber
dioscorea
dodder
sweet flag
polyphenols
senna
peach
indigo leaves
soursop
Agar
Anthraquinone
Ardisia
Amomum
Alexandrian senna
Aloin
Appleblossom Cassia
Asam gelugor
Asteracea
Arabinoxylan
Allium tuberosum
Amor seco
Atractylone
Black Seed
Bifidobacterium
Bifidobacterium adolescentis
Bidens pilosa
Broussonetia
Bishop's Weed
Belleric myrobalan
Bran
Bitter Grass
Bael
Butternut
black salt
Bifidobacterium animalis
Bee products
Bombax
Borassus Palm
Bacteria
Bifidobacteria
Bacillus
Bassia scoparia
Bottle gourd
Borneol
Coconut
Curry leaf
Cascaroside
Cactus
Cynomorium
Citrus
Cantaloupe
Cyclanthera pedata
Chenopodium
Curcuma
Cabbage
Chirata
Clostridium butyricum
Castor Oil
Celosia
Currant
Chondrus
Dianthrone
Date
Eclipta
Fig
Fiber
Galangal
Phosphate Salt
Rhubarb
Wheat
Zucchini

Other health conditions supported by hydroxyanthracene derivatives

Colon (atonic)
Colon (spastic)
Constipation (adults)
Constipation (children)
Digestion (poor)

Products containing hydroxyanthracene derivatives

We currently have no products on Vitabase that contain this ingredient.