Evidence supporting the use of: Isomalto-oligosaccharide
For the health condition: Constipation (children)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Isomalto-oligosaccharide (IMO) is a type of prebiotic dietary fiber commonly added to foods and supplements. Its use for supporting or treating constipation, including in children, has a basis in scientific research. IMOs are not significantly digested in the small intestine; instead, they reach the colon, where they are fermented by beneficial gut bacteria. This fermentation process increases the production of short-chain fatty acids, which can stimulate bowel movements and improve stool consistency.
Several clinical studies have explored the effects of IMO and other prebiotics on bowel function in children. For example, randomized controlled trials have shown that prebiotics such as IMOs can increase stool frequency and improve stool softness in children with functional constipation, though the effect size is generally modest. The mechanism is thought to involve both increasing fecal bulk and enhancing beneficial bacterial populations, such as Bifidobacteria, which are associated with improved gut motility.
However, while there is scientific support for the use of IMOs, the evidence is not as robust or consistent as it is for other fiber sources such as inulin or certain oligosaccharides (e.g., GOS or FOS). The overall rating is moderate (3/5) because, although studies have shown benefit, the number and quality of trials specifically in children are limited, and some studies use mixtures of prebiotics rather than IMO alone. Nonetheless, IMO is regarded as a safe and potentially beneficial adjunct for managing mild pediatric constipation.
More about isomalto-oligosaccharide
More about Constipation (children)
Other ingredients used for Constipation (children)
2'-FucosyllactoseAgar
Alexandrian senna
Allium tuberosum
Almond fruit
Aloe vera
Aloin
alpinia galangal
Amomum
Amor seco
anise
anthraquinone
apple
Appleblossom Cassia
apricot
arabinoxylan
Ardisia
Asam gelugor
Asteraceae
atractylodes
atractylone
Bacillus
bacillus coagulans
bacteria
bael
bamboo
basil
Bassia scoparia
bee products
beet
belleric myrobalan
Bidens pilosa
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
bio ecolian (proprietary)
bishop\'s weed
bitter grass
black salt
black seed
blackberry
blackboard tree
blueberry
Bombax
borassus palm
borneol
bottle gourd
bran
Broussonetia
butternut
bасора
cabbage
cactus
cantaloupe
carrot
cascara sagrada
cascaroside
castor oil
Celosia
chamomile
Chenopodium
chicory
chirata
Chondrus
cinnamon
Citrus
citrus sinensis (proprietary)
Clostridium butyricum
coconut
coconut milk
Coptis chinensis
cowage seed
cucumber
Curcuma
currant
curry leaf
Cyclanthera pedata
Cynomorium
date
dianthrone
dioscorea
dodder
Eclipta
fennel
fiber
fiber blend (proprietary)
fig
Frangula
fructan
fructooligosaccharides (FOS)
fruit
fruit and vegetable blend (proprietary)
galactomannan
galactooligosaccharides
Galangal
Glucofrangulin
grape
green banana
guar gum
Guava
honey
hydroxyanthracene derivatives
Hydroxycellulose
Hygrophila
Indian bael
Indian kinotree
Indian tinospora
indigo leaves
inulin
isomalto-oligosaccharide
Jalap
jujube
jungli-bean
karaya gum
Kefir
lactitol
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus gasseri
Lactobacillus kefiri
Lactobacillus pentosus
Lactobacillus reuteri
Lactococcus rhamnosus
lemon
ligustilides
lodhtree
long pepper
luffa
Methylcellulose
Moringa
Mucilage
Mugwort
Myrobalan
Nettle
nut grass
Nutmeg
Nymphaea nouchali
Oligosaccharides
Operculina turpethum
Ophiopogon
orange
Oryza sativa
Osmanthus
Palmyra
papaya
peach
pear
Phaeophyceae
phellodendron amurense
Phyllanthus
pineapple
Piper nigrum
Piper retrofractum
Plantago
plum fruit
Polygonum
polyphenols
polysaccharides
pomegranate
prebiotic blend (proprietary)
probiotics
prune
psyllium
pumpkin
punarnava
Pyrrosia
raspberry
Rhamnus nakaharai
rhizome
rhubarb
ricinoleic acid
root tuber
Rubiaceae
seaweed
senna
Sennosides
Sesbania
Sete sangrias
Sicklepod
Slippery Elm
slippery elm bark
Solanum indicum
soursop
spinach
squawvine
streptococcus thermophilus
Sulfated polysaccharide
sweet flag
Tamaricaceae
Tamarind
Tea
Triphala
turmeric
vegetable and fruit blend (proprietary)
Watermelon
Wax Gourd
Wheat
Yacon
Yerba buena
Zedoary
Zingerone
Zucchini
Other health conditions supported by isomalto-oligosaccharide
ColitisConstipation (adults)
Constipation (children)
Diabetes
Gas and Bloating
Inflammatory Bowel Disorders
Irritable Bowel Syndrome
Products containing isomalto-oligosaccharide
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Metagenics
GI Sustain™ Powder
Metagenics
PhytoGanix® Tropical Fruit
Metagenics
UltraGI Replenish® Chocolate
Metagenics
UltraGI Replenish Chocolate
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraGI Replenish Vanilla
