Evidence supporting the use of: Lactobacillus gasseri
For the health condition: Constipation (children)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus gasseri is a probiotic bacterium that has been studied for its potential benefits in gastrointestinal health, including the management of constipation in children. The scientific evidence supporting its use for pediatric constipation is limited but present. Some randomized controlled trials (RCTs) and small observational studies have investigated the effects of L. gasseri supplementation in children with functional constipation. For example, a pilot study published in the Journal of Pediatric Gastroenterology and Nutrition (2013) found that children receiving L. gasseri OLL2716 showed some improvement in stool frequency and consistency compared to placebo. Another study demonstrated that L. gasseri, in combination with other probiotic strains, improved symptoms of constipation in children, though it can be challenging to attribute effects solely to L. gasseri in multi-strain formulations.

Despite these promising findings, the overall quality and quantity of evidence are still modest. Most studies have small sample sizes, short durations, or lack replication. The proposed mechanism involves modulation of the gut microbiota, enhancement of intestinal motility, and production of short-chain fatty acids, which may help alleviate constipation. However, major pediatric guidelines do not yet recommend L. gasseri as a first-line therapy for constipation in children due to insufficient robust evidence. In summary, while there is some scientific support for the use of L. gasseri in pediatric constipation, further high-quality research is needed to confirm efficacy and safety.

More about Lactobacillus gasseri
More about Constipation (children)

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alpinia galangal
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