Evidence supporting the use of: Amino Acid Blend/Complex
For the health condition: Convalescence

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Amino acid blends or complexes are supported by scientific evidence for use during convalescence (the period of recovery after illness or surgery). During convalescence, the body's protein requirements often increase due to tissue repair, immune system function, and the restoration of lean body mass lost during illness or immobilization. Several clinical trials and meta-analyses indicate that supplementation with essential amino acids, branched-chain amino acids (BCAAs), or balanced amino acid formulas can help preserve or restore muscle mass and improve functional outcomes in patients recovering from acute illness, surgery, trauma, or prolonged bed rest.

For example, studies in elderly or hospitalized patients have shown that amino acid supplementation can reduce muscle wasting and promote faster recovery of strength and mobility. Specific evidence exists for the use of leucine-enriched amino acid formulas in promoting muscle protein synthesis and attenuating sarcopenia during recovery. Guidelines from clinical nutrition societies such as ESPEN and ASPEN also support the use of amino acid supplementation as part of medical nutrition therapy during convalescence, particularly when dietary intake is insufficient.

However, while the overall quality of evidence is good, outcomes can vary depending on the patient population, type of amino acids used, and baseline nutritional status. Amino acid blends are not a replacement for comprehensive nutritional care but are a scientifically validated adjunct in supporting recovery during convalescence.

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