Cistanche (Cistanche deserticola and related species) has been used in traditional Chinese medicine (TCM) for centuries, particularly as a tonic to strengthen the body during periods of weakness or recovery, which aligns with the concept of convalescence. In classical TCM texts, Cistanche is often described as a "yang tonic" that nourishes the kidneys and replenishes vital essence (jing), with indications including fatigue, debility, and general weakness—common complaints during recovery from illness or injury.

The traditional use of Cistanche for convalescence is primarily based on empirical observations and its reputation as a restorative herb. It has been combined with other herbs in formulas intended to rebuild strength and support the body's recuperative processes. While modern pharmacological research has identified certain bioactive compounds in Cistanche (such as echinacoside and acteoside) with antioxidant, anti-inflammatory, and neuroprotective effects, direct clinical evidence specifically supporting its efficacy in convalescence is limited.

Overall, the use of Cistanche for supporting convalescence is justified mainly by traditional practice and historical precedent, with only modest scientific exploration into its mechanisms and potential benefits. The evidence is stronger in the context of traditional usage rather than rigorous clinical validation.