Evidence supporting the use of: Lactoferrin
For the health condition: Convalescence

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactoferrin is an iron-binding glycoprotein found in various secretory fluids, including milk, and is present in high concentrations in human colostrum. Its use in support of convalescence—the period of recovery after illness or infection—is primarily justified by scientific evidence, although the strength of this evidence is moderate (rated 3 out of 5).

Several studies indicate that lactoferrin has immunomodulatory, antimicrobial, and anti-inflammatory properties. During convalescence, the immune system is often weakened, and the body is vulnerable to secondary infections and inflammation. Lactoferrin has been shown to stimulate the activity of immune cells such as lymphocytes and natural killer cells, enhance the maturation of T-cells, and modulate cytokine production, all of which may help accelerate immune recovery.

Additionally, lactoferrin’s ability to bind free iron can limit bacterial growth and reduce oxidative stress, which is beneficial during the healing process. Clinical trials have explored its use in supporting recovery from infections, with some showing faster normalization of immune markers and reduced inflammation in individuals given lactoferrin supplements.

However, while preclinical and early clinical data are promising, large-scale, high-quality human trials specifically focused on convalescence are limited. Thus, while the scientific rationale is strong and there is supportive evidence, more research is needed to translate these findings into definitive clinical recommendations. Its use is not based on traditional medicine but on contemporary biomedical research.

More about lactoferrin
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Products containing lactoferrin

Metagenics Probioplex® Intensive Care Powder