Evidence supporting the use of: Vitamin C (not specified)
For the health condition: Convalescence

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) has historically been used during convalescence—the period of recovery following illness—based on both its essential role in immune function and its antioxidant properties. The rationale for its use is rooted in the vitamin’s established necessity for normal immune system functioning, collagen synthesis, and tissue repair, which are critical processes during recovery. Scientific studies demonstrate that vitamin C deficiency impairs immunity and wound healing, both important during convalescence. Supplementing vitamin C in deficient individuals or those under increased oxidative stress (e.g., during infection or after surgery) has shown some benefits, such as reducing the duration of respiratory infections and supporting wound healing.

However, the body of evidence supporting vitamin C supplementation for convalescence in otherwise healthy, well-nourished individuals is mixed. Systematic reviews and randomized controlled trials generally do not show significant benefits in speeding recovery or preventing complications in most convalescent populations unless there is a pre-existing deficiency. The strongest effects are seen in those with low baseline vitamin C levels or increased physiological needs. Historically, vitamin C became popular during convalescence due to scurvy prevention and the work of early 20th-century physicians, but modern evidence suggests its benefit is moderate and context-dependent.

Therefore, while there is a scientific rationale and some supporting evidence for vitamin C use during convalescence, particularly in the presence of deficiency or elevated requirements, the overall evidence is not robust for routine supplementation in all recovering patients.

More about Vitamin C (not specified)
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