Evidence supporting the use of: Rhodiola
For the body system: Cortisol

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Rhodiola rosea is an adaptogenic herb traditionally used in Russia and Scandinavian countries to reduce fatigue and enhance resilience to stress. Its relevance to the "cortisol body system" stems from evidence that it may modulate the body's stress response, including effects on cortisol, the primary stress hormone. Several randomized controlled trials and animal studies have investigated Rhodiola’s impact on stress and cortisol. Some studies have demonstrated that supplementation with Rhodiola can reduce the rise in cortisol during acute stress, potentially supporting healthier cortisol rhythms. For example, a 2009 double-blind study in "Planta Medica" found that Rhodiola extract significantly reduced salivary cortisol levels in stressed healthcare workers. Another review (2011, "Phytomedicine") reported that Rhodiola may normalize cortisol levels and improve symptoms of stress-induced fatigue. However, the body of evidence is still limited by small sample sizes, short durations, and heterogeneity in study design. While there is scientific support for Rhodiola’s stress-modulating effects and influence on cortisol, these findings should be considered preliminary. Larger, high-quality clinical trials are needed to better understand its mechanism and efficacy. Overall, Rhodiola is scientifically used to support the stress response and modulate cortisol, but the evidence is moderate rather than strong.

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