Evidence supporting the use of: Rosabin
For the body system: Cortisol

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Rosavin is one of the primary active compounds found in Rhodiola rosea, an adaptogenic herb traditionally used to support physical and mental resilience. Scientifically, several studies have investigated Rhodiola’s impact on the body’s stress response, particularly its effects on the hypothalamic-pituitary-adrenal (HPA) axis, which regulates cortisol production. Clinical trials and animal studies suggest that Rhodiola extracts standardized for rosavin content may help modulate cortisol levels in response to stress. For example, a 2009 double-blind, placebo-controlled study in Phytomedicine found that Rhodiola supplementation reduced stress-induced fatigue and appeared to normalize elevated cortisol levels in participants exposed to chronic stress. Another study published in Planta Medica (2003) also reported that Rhodiola extract helped balance the secretion of stress hormones including cortisol. While most of these studies use whole plant extracts rather than isolated rosavin, the standardized content of rosavin is considered a marker for efficacy. However, the precise mechanisms and the relative contribution of rosavin versus other constituents (such as salidroside) are not fully elucidated. The evidence base is moderate, with supportive but not definitive clinical trials, so the rating is 3 out of 5. Overall, there is scientific support for the use of rosavin-containing Rhodiola extracts in modulating the cortisol body system, though more research is needed to isolate rosavin’s specific effects.

More about Rosabin
More about Cortisol

Other body systems supported by Rosabin

Adrenal Cortex
Brain
Cortisol
Glandular System
Heart

Products containing Rosabin

We currently have no products on Vitabase that contain this ingredient.