Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Perilla (Perilla frutescens) has a long history in traditional East Asian medicine, especially in Chinese herbal medicine, where its leaves (known as Zi Su Ye, 紫苏叶) are used to treat respiratory issues, including coughs associated with “dampness,” a traditional pathological concept. In Traditional Chinese Medicine (TCM), a “damp cough” is characterized by symptoms such as a productive cough with phlegm, chest congestion, and a sensation of heaviness. Perilla leaf is believed to alleviate these symptoms by dispersing wind-cold, resolving dampness, and regulating the flow of qi in the lungs.

Historically, perilla has been included in various classical herbal formulas targeting coughs with phlegm, and is often combined with other herbs to enhance its effects. The traditional rationale is based on empirical use rather than modern clinical trials. Some phytochemical studies have identified anti-inflammatory and bronchodilatory compounds in perilla, such as perillaldehyde and flavonoids, which could theoretically support its use for respiratory symptoms, but robust clinical evidence specific to “damp cough” is lacking.

Overall, the use of perilla for “cough (damp)” is primarily justified by traditional practices rather than strong scientific evidence. There are few modern clinical studies specifically investigating perilla’s efficacy for this condition, so the evidence rating remains low, despite its widespread use in TCM.

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