Evidence supporting the use of: Vasicine
For the health condition: Cough (damp)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Vasicine is an alkaloid found primarily in the plant Adhatoda vasica (also known as Malabar nut). Its use for treating cough, particularly productive or "damp" cough, is supported both by traditional Ayurvedic medicine and by scientific studies, though the scientific evidence is moderate rather than robust. Vasicine exhibits bronchodilatory, expectorant, and mild antitussive properties. Several pharmacological studies have demonstrated that vasicine stimulates bronchial secretions, helping to liquefy and expel mucus, which is beneficial in cases of cough associated with excessive phlegm. Animal studies and limited human data support its mucolytic and bronchodilating effects, aligning with its traditional usage for respiratory ailments.
In addition to expectorant action, vasicine has been shown to possess anti-inflammatory and antimicrobial activities, which may contribute to symptom relief in respiratory tract infections. However, high-quality randomized controlled trials in humans are limited, and most of the available evidence is preclinical or derives from traditional use. For this reason, the scientific evidence rating is moderate (3 out of 5).
In summary, vasicine is justified as a treatment for cough with phlegm ("damp cough") based on both longstanding traditional use and moderate scientific validation, particularly for its expectorant and bronchodilatory actions.
Other ingredients used for Cough (damp)
AdenophoraAllium tuberosum
Aloe vera
alpinia galangal
Anamarrhena
anise
asafoetida
Asam gelugor
Asarum heterotropoides
Asarum sieboldii
atractylodes
atractylone
bael
balloon flower
black currant
black pepper
butternut
Chekiang Fritillary
chen pi
Chondrus
cineole
clove
coltsfoot
common madia
cowage seed
Dichrostachys glomerata
elderberry
eucalyptus
ferula assafoetida
fritillaria
Galangal
Gallesia
garlic bulb
ginger
glehnia root
green tea
Grindelia
honey
horehound
hyssop
inula racemosa
Ivy
Japanese kadsura
Javanese Long Pepper
licorice root
Ligusticum
ligustilides
Lilium polyphyllum
long pepper
loquat
Loranthus
Mentha haplocalyx
Monoterpenes
Mucolase
oregano
Osha
parsley
pear
perilla
phellodendron amurense
Pinellia ternata
pistacia integerrima gall
Platycodon
platycodon root
pomegranate
quercetin
radish
ravinsara
rhizome
Shogaol
Solanaceae
Sundew
Tamarind
thyme
turmeric
Vasicine
Vasicinol
Vasicinone
Visnea Mocanera
Wax Gourd
Zedoary
zhejiang fritillary
Zinc
