Evidence supporting the use of: Atractylone
For the health condition: Cough (dry)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Atractylone is a sesquiterpenoid compound found in the rhizome of Atractylodes species, particularly Atractylodes macrocephala, a plant commonly used in Traditional Chinese Medicine (TCM). Historically, the dried rhizome of Atractylodes (known as "Bai Zhu" in Chinese) has been used to strengthen the spleen, dry dampness, and support the body's "qi." While its primary applications focus on digestive health and improving energy, some traditional herbal formulas that include Atractylodes are used for coughs or respiratory issues, particularly when these are associated with underlying spleen deficiency or dampness according to TCM theory. The use of atractylone itself specifically for dry cough, however, is not prominent in classical texts, and its role in cough management appears to be secondary or supportive within multi-herb formulas rather than as a direct antitussive agent.

From a scientific perspective, there is limited research on atractylone’s direct effects on cough or respiratory symptoms. Most modern pharmacological studies of atractylone focus on its anti-inflammatory, antioxidant, and gastrointestinal effects. There is a lack of clinical trials or experimental studies specifically validating its efficacy for dry cough. Therefore, the justification for using atractylone for dry cough is primarily based on traditional herbal practice, with minimal direct scientific evidence.

More about Atractylone
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