Evidence supporting the use of: Cineole
For the health condition: Cough (dry)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Cineole (also known as eucalyptol) is a monoterpenoid compound found predominantly in eucalyptus oil. Its use for treating or supporting dry cough is supported by moderate scientific evidence. Cineole exerts its effects through several mechanisms, including mucolytic (mucus-thinning), bronchodilatory, and anti-inflammatory actions. Several clinical trials and reviews have shown that cineole can reduce the frequency and severity of cough in patients with respiratory conditions, such as bronchitis and asthma, which often include symptoms of dry cough.
For example, randomized controlled studies have demonstrated that oral cineole (commonly at doses of 200 mg three times daily) can significantly decrease cough frequency and improve pulmonary function in patients with acute and chronic bronchitis. Its efficacy appears to stem from its ability to reduce airway inflammation and increase the secretion of less viscous mucus, thus soothing irritation in the respiratory tract that can provoke dry cough. Additionally, cineole has been shown to exert antimicrobial effects, which may be beneficial if cough is associated with mild infections.
While the evidence base is not as robust as for some conventional antitussives, and most studies focus on broader respiratory conditions rather than isolated dry cough, reviews in reputable journals and meta-analyses support the beneficial effects of cineole in respiratory tract diseases with cough as a prominent symptom. Therefore, its use is considered scientifically justified, with a moderate evidence rating.
Other ingredients used for Cough (dry)
aloe veraalpha-pinene
apple
waterhyssop
benegut perilla (proprietary)
beta-pinene
black currant
black pepper
radish
Indian frankincense
cat's claw
Chinese salvia root
cinnamon
clove
cowage seed
turmeric
elderberry
garlic bulb
ginger
glehnia root
greek mountain tea
onion
green tea
heartwood
Indian tinospora
jujube
lemon
licorice root
marshmallow
nettle
ophiopogon root
oregano
parsley
pear
phellodendron amurense
platycodon root
plum fruit
polygala root
pomegranate
thyme
vitamin C
zhejiang fritillary
zinc
sarsaparilla
boneset
mullein
tangerine
hyssop
atractylodes
Indian bael
malabar nut
alpinia galangal
hedychium spicatum
inula racemosa
anise
pistacia integerrima gall
fumaria parviflora
fritillaria
yerba santa
elecampane
dodder
sweet flag
menthol oil
Alcohol
Agastache
Anamarrhena
Ambergris
acacia
Asarum heterotropoides
Aconite
Asafoetida
Aerva lanata
Asam gelugor
Adenophora
Allium tuberosum
Asarum sieboldii
Atractylone
Black Seed
Bermuda Grass
Bryonia
Bayleaf
Bael
Butternut
Baccharoides anthelmintica
black salt
Bee products
Buddha's Hand
banana
Bassia scoparia
Burning Bush
Balloon Flower
Belamcanda
Bergenia
Cactus
Citron
Citrus
Cineole
Capsaicin
Cistus
Cubeb
Cowslip
Chaenomeles lagenaria
Calamus
Cinnamaldehyde
Clerodendrum indicum
Dragonhead
Diterpenes
Dichrostachys glomerata
Echinacea
Elder
Ephedrine
Poppy
Other health conditions supported by Cineole
Allergies (respiratory)Asthma
Bronchitis
Colds (decongestant)
Colds (general)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Inflammation
Influenza
Laryngitis
Rhinitis
Rhinitis, Allergic
Sinus Infection
Wheezing