Evidence supporting the use of: Cineole
For the health condition: Cough (dry)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Cineole (also known as eucalyptol) is a monoterpenoid compound found predominantly in eucalyptus oil. Its use for treating or supporting dry cough is supported by moderate scientific evidence. Cineole exerts its effects through several mechanisms, including mucolytic (mucus-thinning), bronchodilatory, and anti-inflammatory actions. Several clinical trials and reviews have shown that cineole can reduce the frequency and severity of cough in patients with respiratory conditions, such as bronchitis and asthma, which often include symptoms of dry cough.
For example, randomized controlled studies have demonstrated that oral cineole (commonly at doses of 200 mg three times daily) can significantly decrease cough frequency and improve pulmonary function in patients with acute and chronic bronchitis. Its efficacy appears to stem from its ability to reduce airway inflammation and increase the secretion of less viscous mucus, thus soothing irritation in the respiratory tract that can provoke dry cough. Additionally, cineole has been shown to exert antimicrobial effects, which may be beneficial if cough is associated with mild infections.
While the evidence base is not as robust as for some conventional antitussives, and most studies focus on broader respiratory conditions rather than isolated dry cough, reviews in reputable journals and meta-analyses support the beneficial effects of cineole in respiratory tract diseases with cough as a prominent symptom. Therefore, its use is considered scientifically justified, with a moderate evidence rating.
Other ingredients used for Cough (dry)
AcaciaAconite
Adenophora
Aerva lanata
Agastache
Alcohol
Allium tuberosum
Aloe vera
alpha-pinene
alpinia galangal
ambergris
Anamarrhena
anise
apple
asafoetida
Asam gelugor
Asarum heterotropoides
Asarum sieboldii
atractylodes
atractylone
Baccharoides anthelmintica
bael
balloon flower
banana
Bassia scoparia
bayleaf
bee products
Belamcanda
benegut perilla (proprietary)
Bergenia
bermuda grass
beta-pinene
black currant
black pepper
black salt
black seed
boneset
Bryonia
Buddha\'s hand
burning bush
butternut
cactus
calamus
capsaicin
cat's claw
Chaenomeles lagenaria
Chinese salvia root
cineole
cinnamaldehyde
cinnamon
Cistus
citron
Citrus
Clerodendrum indicum
clove
cowage seed
cowslip
cubeb
Dichrostachys glomerata
diterpenes
dodder
dragonhead
Echinacea
Elder
elderberry
elecampane
ephedrine
fernbush
flavoglycosides
fringed pink
fritillaria
fritillary
fruit
Fumaria parviflora
Gallesia
garlic bulb
ginger
Glehnia littoralis
glehnia root
Glycyrrhetinic acid
Greek mountain tea
green tea
Guava
gum
heartwood
Hedychium spicatum
Hempnettle
honey
honey loquat syrup
hyssop
Ilex
Indian bael
Indian frankincense
Indian tinospora
inula racemosa
Japanese kadsura
Javanese Long Pepper
jujube
Khella
Lactucarium
Large-leaved linden
lemon
licorice root
Ligusticum
Lilium polyphyllum
linden
Lindera
long pepper
loquat
Loranthus
luffa
lungwort
mace
Maidenhair Fern
malabar nut
Marshmallow
Melia
Mentha haplocalyx
Menthol oil
Mucilage
Mullein
Nettle
Nigella seed
Nutmeg
onion
Ophiopogon
ophiopogon root
oregano
Osha
Osmanthus
Palmyra
Paris polyphylla
parsley
pear
Pelargonium
Pepper
Phellodendron
phellodendron amurense
Pimpinella
Piper chaba
pistacia integerrima gall
Platycodon
platycodon root
plum fruit
Polygala
polygala root
polymorpha
pomegranate
poppy
prepared aconite tuber
radish
ravinsara
Rhododendron
Sabadilla
sarsaparilla
Sedanenolide
Sete sangrias
Shogaol
Solanaceae
Stemona
Stephania root
Sundew
sweet flag
Tamarind
Tea
Terpenoids
Theobromine
thyme
Thymol
Thymoquinone
Tonka Bean
Tragacanth
turmeric
Vasicine
Vasicinol
Vasicinone
vitamin C
Vladimiria souliei
Waterhyssop
Wax Gourd
Yerba santa
Zedoary
zhejiang fritillary
Zinc
Zingerone
Other health conditions supported by cineole
Allergies (respiratory)Asthma
Bronchitis
Colds (decongestant)
Colds (general)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Inflammation
Influenza
Laryngitis
Rhinitis
Rhinitis, Allergic
Sinus Infection
Wheezing
