Evidence supporting the use of: Glycyrrhiza (unspecified)
For the health condition: Cough (dry)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Glycyrrhiza, commonly known as licorice root, has a long history of use in traditional medicine systems, particularly in Traditional Chinese Medicine (TCM), Ayurveda, and various folk medicine traditions, for the management of coughs, including dry coughs. The root contains a variety of active compounds, most notably glycyrrhizin, which is thought to have demulcent (soothing) and anti-inflammatory properties. Historically, decoctions or syrups made from licorice root have been used to soothe irritated mucous membranes of the respiratory tract, thereby alleviating cough and throat discomfort.

While there is some preclinical evidence suggesting that licorice extracts can inhibit cough reflexes and reduce airway inflammation in animal models, robust clinical trials in humans are limited. The majority of the support for its use comes from case reports, traditional herbal formulations, and observational studies rather than high-quality randomized controlled trials. In several Asian countries, licorice is still a component of over-the-counter cough remedies and is included in various compound herbal formulations for respiratory complaints.

In summary, the use of Glycyrrhiza for dry cough is primarily supported by traditional practices, with moderate indirect evidence from laboratory and limited human studies. More rigorous scientific evidence would be necessary to confirm its efficacy and safety for this indication.

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