Evidence supporting the use of: Menthol
For the health condition: Cough (dry)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Menthol is commonly used in over-the-counter remedies for dry cough, such as lozenges and topical ointments. Its use is supported by scientific evidence, though the strength of that evidence is moderate. Menthol acts as a counterirritant, producing a cooling sensation by activating the TRPM8 receptors in the respiratory tract. This sensation can temporarily suppress the cough reflex and provide subjective relief from throat irritation, which is often a trigger for dry cough.
Several studies have demonstrated that menthol can reduce cough sensitivity in both healthy volunteers and individuals with acute cough. For example, a 2012 study published in "Chest" found that inhaled menthol reduced cough sensitivity to capsaicin in healthy adults. However, systematic reviews and guidelines note that while menthol provides symptomatic relief, there is limited evidence from large, high-quality randomized controlled trials to fully endorse its effectiveness for all patients with dry cough. Most of its use is based on its ability to soothe the throat and its subjective benefits, rather than robust evidence for altering the underlying cause of cough.
In summary, menthol’s use for dry cough is scientifically plausible and supported by moderate evidence for symptomatic relief, but further research is needed to clarify its efficacy compared to other treatments.
Other ingredients used for Cough (dry)
aloe veraalpha-pinene
apple
waterhyssop
benegut perilla (proprietary)
beta-pinene
black currant
black pepper
radish
Indian frankincense
cat's claw
Chinese salvia root
cinnamon
clove
cowage seed
turmeric
elderberry
garlic bulb
ginger
glehnia root
greek mountain tea
onion
green tea
heartwood
Indian tinospora
jujube
lemon
licorice root
marshmallow
nettle
ophiopogon root
oregano
parsley
pear
phellodendron amurense
platycodon root
plum fruit
polygala root
pomegranate
thyme
vitamin C
zhejiang fritillary
zinc
sarsaparilla
boneset
mullein
tangerine
hyssop
atractylodes
Indian bael
malabar nut
alpinia galangal
hedychium spicatum
inula racemosa
anise
pistacia integerrima gall
fumaria parviflora
fritillaria
yerba santa
elecampane
dodder
sweet flag
menthol oil
Alcohol
Agastache
Anamarrhena
Ambergris
acacia
Asarum heterotropoides
Aconite
Asafoetida
Aerva lanata
Asam gelugor
Adenophora
Allium tuberosum
Asarum sieboldii
Atractylone
Black Seed
Bermuda Grass
Bryonia
Bayleaf
Bael
Butternut
Baccharoides anthelmintica
black salt
Bee products
Buddha's Hand
banana
Bassia scoparia
Burning Bush
Balloon Flower
Belamcanda
Bergenia
Cactus
Citron
Citrus
Cineole
Capsaicin
Cistus
Cubeb
Cowslip
Chaenomeles lagenaria
Calamus
Cinnamaldehyde
Clerodendrum indicum
Dragonhead
Diterpenes
Dichrostachys glomerata
Echinacea
Elder
Ephedrine
Poppy
Other health conditions supported by Menthol
Abdominal PainAllergies (respiratory)
Athletic and Exercise Aids
Backache
Bites and Stings
Bronchitis
Canker Sores
Colds (decongestant)
Colds (general)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Cough (dry)
Cough (general)
Cough (spastic)
Dermatitis
Digestion (poor)
Eczema
Exercise