Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Ophiopogon root (Ophiopogon japonicus, known as Mai Men Dong in Traditional Chinese Medicine, TCM) has a long history of use in East Asian herbal medicine, particularly for treating dry cough and other symptoms linked to dryness of the lungs. In TCM theory, ophiopogon root is known for its ability to "nourish Yin," moisten dryness, and clear heat from the lungs and stomach. This makes it a common ingredient in herbal formulas prescribed for dry, irritating coughs—especially those associated with yin deficiency, throat dryness, or hoarseness. Classical medical texts such as the "Shennong Bencao Jing" and "Compendium of Materia Medica" describe its use for conditions involving thirst, cough, and dry throat.

Modern pharmacological studies offer some support for these traditional uses, suggesting that ophiopogon root contains steroidal saponins, polysaccharides, and homoisoflavonoids, which may have anti-inflammatory, immunomodulatory, and mucoprotective effects. Limited animal studies and in vitro research indicate that extracts of ophiopogon may help protect respiratory tissues and reduce inflammation. However, robust clinical trials in humans specifically evaluating its efficacy for dry cough are lacking. Thus, the main justification for its use remains traditional, with moderate evidence from historical usage and preliminary pharmacological studies, but limited confirmation from contemporary clinical research.

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