Evidence supporting the use of: Sedanenolide
For the health condition: Cough (dry)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Sedanenolide is a phthalide compound found in some plants, notably in Apium graveolens (celery) and Ligusticum species. Its use to support or treat dry cough primarily originates from traditional herbal medicine, especially within certain European and Asian folk practices where celery seed and related botanicals were used as general remedies for respiratory discomfort. However, there is little to no direct historical documentation specifically attributing anti-tussive (cough-suppressant) effects to sedanenolide itself, but rather to the whole plant or extract.

On the scientific front, there is a lack of robust clinical research or pharmacological studies demonstrating that sedanenolide, as a single compound, has efficacy in treating dry cough. Most available research on sedanenolide has focused on its potential anti-inflammatory, anti-spasmodic, and mild sedative properties, which might indirectly support traditional uses for relieving cough or respiratory irritation, but the evidence is sparse and not specific to dry cough.

In summary, the use of sedanenolide for dry cough is supported by tradition rather than scientific validation, and the direct evidence for this specific use is weak.

More about Sedanenolide
More about Cough (dry)

Products containing Sedanenolide

We currently have no products on Vitabase that contain this ingredient.