Evidence supporting the use of: Stephania root
For the health condition: Cough (dry)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Stephania root (from species such as Stephania tetrandra and Stephania glabra) has a long history of use in traditional Chinese medicine (TCM) and other Asian herbal practices. In TCM, Stephania root—often referred to as "Fang Ji"—is used to "dispel wind and dampness," alleviate pain, and sometimes to address symptoms such as cough, particularly when associated with dryness or irritation. The traditional rationale is based on its supposed ability to clear heat and remove toxins, which are believed to contribute to dryness and cough in TCM theory.
Despite its historical use, there is limited scientific research specifically evaluating Stephania root for the treatment of dry cough in humans. Most available studies focus on its anti-inflammatory, analgesic, and immunomodulatory properties, with some laboratory and animal model evidence suggesting that certain alkaloids (like tetrandrine) found in Stephania may have effects on airway inflammation or smooth muscle relaxation. However, these findings have not been robustly translated into clinical trials for cough—dry or otherwise.
In summary, the use of Stephania root for dry cough is primarily justified by traditional herbal practices rather than modern scientific evidence. The evidence rating given (2/5) reflects a moderate degree of longstanding traditional use but a lack of strong clinical or pharmacological data supporting its efficacy specifically for dry cough.
Other ingredients used for Cough (dry)
aloe veraalpha-pinene
apple
waterhyssop
benegut perilla (proprietary)
beta-pinene
black currant
black pepper
radish
Indian frankincense
cat's claw
Chinese salvia root
cinnamon
clove
cowage seed
turmeric
elderberry
garlic bulb
ginger
glehnia root
greek mountain tea
onion
green tea
heartwood
Indian tinospora
jujube
lemon
licorice root
marshmallow
nettle
ophiopogon root
oregano
parsley
pear
phellodendron amurense
platycodon root
plum fruit
polygala root
pomegranate
thyme
vitamin C
zhejiang fritillary
zinc
sarsaparilla
boneset
mullein
tangerine
hyssop
atractylodes
Indian bael
malabar nut
alpinia galangal
hedychium spicatum
inula racemosa
anise
pistacia integerrima gall
fumaria parviflora
fritillaria
yerba santa
elecampane
dodder
sweet flag
menthol oil
Alcohol
Agastache
Anamarrhena
Ambergris
acacia
Asarum heterotropoides
Aconite
Asafoetida
Aerva lanata
Asam gelugor
Adenophora
Allium tuberosum
Asarum sieboldii
Atractylone
Black Seed
Bermuda Grass
Bryonia
Bayleaf
Bael
Butternut
Baccharoides anthelmintica
black salt
Bee products
Buddha's Hand
banana
Bassia scoparia
Burning Bush
Balloon Flower
Belamcanda
Bergenia
Cactus
Citron
Citrus
Cineole
Capsaicin
Cistus
Cubeb
Cowslip
Chaenomeles lagenaria
Calamus
Cinnamaldehyde
Clerodendrum indicum
Dragonhead
Diterpenes
Dichrostachys glomerata
Echinacea
Elder
Ephedrine
Poppy
Other health conditions supported by Stephania root
Abdominal PainAsthma
Bronchitis
Cough (dry)
Cough (general)
Fever
Headache (general)
Indigestion
Infection
Inflammation
Nausea and Vomiting
Pain (general remedies for)
Rashes and Hives
Wounds and Sores