Evidence supporting the use of: Licorice root
For the health condition: Cough (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Licorice root (Glycyrrhiza glabra) has a long history of use as a remedy for coughs and other respiratory ailments in traditional medicine systems such as Traditional Chinese Medicine (TCM) and Ayurveda. Its sweet, soothing properties are thought to help relieve throat irritation and suppress coughing. Historically, licorice root was included in cough syrups and lozenges for these reasons.
Scientifically, licorice root contains several active compounds, such as glycyrrhizin and liquiritin, which exhibit anti-inflammatory, demulcent, and expectorant properties. Laboratory studies and a limited number of clinical trials suggest that licorice root extracts can reduce inflammation in the airways, thin mucus, and soothe sore throats. For example, a few small human studies have shown that licorice gargles can reduce postoperative sore throat and cough symptoms. Additionally, in vitro studies indicate that licorice compounds may inhibit certain respiratory viruses and bacteria.
However, the clinical evidence supporting licorice root’s effectiveness for cough is limited and not robust. Most studies are small, short-term, or not well-controlled. Systematic reviews conclude that while there is some promise, more rigorous, large-scale human trials are needed to determine efficacy and safety for cough treatment. Importantly, excessive or prolonged use of licorice root can cause side effects such as hypertension and hypokalemia due to glycyrrhizin content.
In summary, licorice root’s use for cough is supported by both traditional use and a modest amount of scientific evidence, but the evidence is currently not strong enough for definitive clinical recommendations.
Other ingredients used for Cough (general)
allspicealoe vera
alpha-pinene
apple
waterhyssop
bamboo
basil
benegut perilla (proprietary)
beta-pinene
black cumin
black currant
black pepper
radish
Indian frankincense
carrot
cassia bark
cat's claw
chen pi
Chinese salvia root
cinnamon
clove
cowage seed
turmeric
elderberry
fennel
garlic bulb
ginger
glehnia root
grape
greek mountain tea
onion
green tea
heartwood
Indian tinospora
jujube
lemon
licorice root
lovage
marshmallow
nettle
ophiopogon root
orange
oregano
parsley
pear
perilla
phellodendron amurense
platycodon root
plum fruit
polygala root
pomegranate
pumpkin
raspberry
spearmint leaf
sphaeranthus indicus
thyme
vitamin C
zhejiang fritillary
zinc
sarsaparilla
boneset
mullein
tangerine
hyssop
atractylodes
lobelia
capsicum
Indian bael
neem tree
malabar nut
alpinia galangal
ferula assafoetida
hedychium spicatum
inula racemosa
anise
pistacia integerrima gall
punarnava
fumaria parviflora
prickly ash
fritillaria
lemongrass
yerba santa
elecampane
coltsfoot
root tuber
silk tree
juniper berries
amber
dodder
sweet flag
hyacinth bean
eucalyptus
menthol oil
peach
abies spectabilis
horehound
soursop
Alcohol
Aralia
Apple Cider Vinegar
Agastache
Anamarrhena
Alpha-terpineol
Ambergris
Ardisia
Angelica
acacia
Agave
Allicin
Anamu
Abrus
Alchornea
Asarum heterotropoides
Albizia
Aconite
Asafoetida
Ajuga
Andrographolide
Aerva lanata
Agarwood
Asam gelugor
Arrowroot
Andrographis
Alsonia scholaris
Allyl Sulfide
Aspen
Adenophora
Allium tuberosum
Amor seco
Aniseed myrtle
Asarum sieboldii
Alantolactone
Atractylone
Black Seed
Bermuda Grass
Bryonia
Blepharis
Bayleaf
Blackbrush
Big Quaking Grass
Bougainvillea
Bael
Butternut
berry
Baccharoides anthelmintica
black salt
Bee products
Borassus Palm
Buddha's Hand
Borassus aethiopum
Borage
banana
Bassia scoparia
Burning Bush
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Boerhavia diffusa
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Capsaicin
Chenopodium
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Common madia
Cubeb
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Chaenomeles lagenaria
Calamus
Coin-leaf desmodium
Cyanthillium cinereum
Cinnamaldehyde
Costus
Chekiang Fritillary
cola nut
Celosia
Clerodendrum indicum
Culvers Root
Currant
Chondrus
Dragonhead
Diterpenes
Desmodium
Dichrostachys glomerata
Empresstree
English Horsemint
Echinacea
Elder
European Field Elm
Ephedrine
Embelia
Fig
Garlic
Galangal
Himalayan Salt
Ivy
Lily
Poppy
Rose
Spikenard
Sumac
Zucchini
Other health conditions supported by licorice root
Abdominal PainAbrasions
Abscesses
Acid Indigestion
Acne
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Addison's Disease
Adenitis
Adrenal Fatigue
Afterbirth Pain
Age Spots
Allergies (respiratory)
Amenorrhea
Anal Fistula or Fissure
Anemia
Appetite (deficient)
Asthma
Autoimmune Disorders
Bronchitis
Canker Sores
Chemotherapy (reducing side effects)
Chicken Pox
Cholera
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Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
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Colic (adults)
Colic (children)
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Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (lymphatic)
Congestion (sinus)
Constipation (adults)
Contagious Diseases
Convalescence
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cramps (menstrual)
Crohn's Disease
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Cytomealovirus
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Endometriosis
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Epstein Barr Virus
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Gall Stones
Gas and Bloating
Gastritis
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Goiter
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Hair (loss or thinning)
Hair Care (general)
Halitosis
Hangover
Headache (general)
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Headache (tension)
Heart (weakness)
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Overacidity
Pertussis
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PMS (general)
Pneumonia
Poison Ivy or Oak
Rashes and Hives
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Sore Throat
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Products containing licorice root
Vitabase
7 Day Colon Cleanse
Pure Encapsulations
ADR Formula®
Pure Encapsulations
ADR Formula®
Designs For Health
Adrenotoneâ„¢
Designs For Health
Adrenotoneâ„¢
Vitabase
Blood Sugar Formula
Metagenics
CandiBactin BR
Metagenics
CandiBactin-BR
Pure Encapsulations
DGL Plus®
Pure Encapsulations
DGL Plus®
Designs For Health
DGL Synergyâ„¢
Metagenics
Echinacea Synergy
Integrative Therapeutics
EHB
Pure Encapsulations
EpiIntegrity
Metagenics
Essential Defense®
Pure Encapsulations
G.I. Fortify
Designs For Health
GastroMend-HPâ„¢
Designs For Health
GastroMend-HPâ„¢
Thorne
GI Relief GI-Encap
Designs For Health
GI Revive®
Designs For Health
GI Revive®
Metagenics
Glutagenics® powder
Integrative Therapeutics
Heartburn Advantage
Pure Encapsulations
Heartburn Essentials
Pure Encapsulations
Heartburn Essentials
Metagenics
Licorice Plus®
Vitabase
Life's Essentials Plus
Douglas Laboratories
Pylori-Plex
Integrative Therapeutics
Rhizinate
Integrative Therapeutics
Rhizinate-FF
Integrative Therapeutics
Similase Sensitive Stomach
Integrative Therapeutics
Similase Sensitive Stomach
Thorne
Stress Balance Phytisone
Integrative Therapeutics
Super Milk Thistle X
Vitabase
Women's Support