Evidence supporting the use of: Allyl Sulfide
For the health condition: Cough (spastic)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Allyl sulfide, a compound found predominantly in garlic and related Allium species, has been used traditionally in various systems of medicine for respiratory ailments, including coughs (sometimes referred to as "spastic" coughs, which are characterized by sudden, involuntary coughing fits). Historical and ethnobotanical records indicate that preparations containing garlic or its extracts have been recommended for cough relief in traditional Chinese, Ayurvedic, and European herbal medicine. The presumed benefits are attributed to garlic’s volatile sulfur compounds, among which allyl sulfide is a key component, thought to have antimicrobial and mild expectorant properties.

However, direct scientific evidence specifically supporting the use of isolated allyl sulfide for spastic cough is lacking. While some in vitro and animal studies suggest that garlic extracts may possess antitussive (cough-suppressing) and anti-inflammatory activities, these effects have not been conclusively linked to allyl sulfide alone, nor have they been confirmed in rigorous human clinical trials for cough. Thus, the use of allyl sulfide for spastic cough is justified mainly by traditional usage rather than strong scientific validation, and the evidence rating is low.

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