Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Boneset (Eupatorium perfoliatum) has a long history of use in traditional herbal medicine, particularly by Native American peoples and later by European settlers in North America. It was commonly used to treat a variety of febrile illnesses, including influenza, colds, and coughs—especially those described as "spastic" or involving spasmodic coughing fits. The plant's use as a remedy for cough is based primarily on traditional knowledge rather than robust scientific evidence. Historical herbal texts attribute expectorant, diaphoretic, and antispasmodic properties to boneset, making it a popular remedy for respiratory complaints in the 18th and 19th centuries. Modern scientific evaluation of boneset for cough is limited. While some in vitro studies indicate that extracts of boneset possess mild anti-inflammatory and immunomodulatory activity, there are no well-controlled clinical trials directly validating its efficacy for spastic cough or other respiratory conditions. Potential bioactive compounds such as flavonoids and sesquiterpene lactones may contribute to its traditional uses, but these have not been conclusively linked to antitussive effects in humans. Safety concerns also exist regarding long-term or high-dose use due to the presence of potentially hepatotoxic pyrrolizidine alkaloids. In summary, the use of boneset for spastic cough is rooted in tradition with only limited and indirect scientific support.

More about boneset
More about Cough (spastic)

Other ingredients used for Cough (spastic)

Other health conditions supported by boneset

Products containing boneset